Linear elastic and elastic-plastic fracture mechanics. Experimental methods. Microstructural effects on fracture …
Linear elastic and elastic-plastic fracture mechanics. Experimental methods. Microstructural effects on fracture in metals, ceramics, polymers, thin films, biological materials and composites. Toughening mechanisms. Crack growth resistance and creep fracture. Interface fracture mechanics. Fatigue damage and dislocation substructures in single crystals. Stress- and strain-life approach to fatigue. Fatigue crack growth models and mechanisms. Variable amplitude fatigue. Corrosion fatigue. Case studies of fracture and fatigue in structural, bioimplant, and microelectronic components.
Since the discovery of the structure of the DNA double helix in …
Since the discovery of the structure of the DNA double helix in 1953 by Watson and Crick, the information on detailed molecular structures of DNA and RNA, namely, the foundation of genetic material, has expanded rapidly. This discovery is the beginning of the "Big Bang" of molecular biology and biotechnology. In this seminar, students discuss, from a historical perspective and current developments, the importance of pursuing the detailed structural basis of genetic materials.
Are you interested in investigating how nature engineers itself? How engineers copy …
Are you interested in investigating how nature engineers itself? How engineers copy the shapes found in nature ("biomimetics")? This Freshman Seminar investigates why similar shapes occur in so many natural things and how physics changes the shape of nature. Why are things in nature shaped the way they are? How do birds fly? Why do bird nests look the way they do? How do woodpeckers peck? Why can't trees grow taller than they are? Why is grass skinny and hollow? What is the wood science behind musical instruments? Questions such as these are the subject of biomimetic research and they have been the focus of investigation in this course for the past three years.
Like transistors in a computer, synapses perform complex computations and connect the …
Like transistors in a computer, synapses perform complex computations and connect the brain's non-linear processing elements (neurons) into a functional circuit. Understanding the role of synapses in neuronal computation is essential to understanding how the brain works. In this course students will be introduced to cutting-edge research in the field of synaptic neurophysiology. The course will cover such topics as synapse formation, synaptic function, synaptic plasticity, the roles of synapses in higher cognitive processes and how synaptic dysfunction can lead to disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
The need to identify sustainable forms of energy as an alternative to …
The need to identify sustainable forms of energy as an alternative to our dependence on depleting worldwide oil reserves is one of the grand challenges of our time. The energy from the sun converted into plant biomass is the most promising renewable resource available to humanity. This seminar will examine each of the critical steps along the pathway towards the conversion of plant biomass into ethanol. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Fundamentals of Biology focuses on the basic principles of biochemistry, molecular biology, …
Fundamentals of Biology focuses on the basic principles of biochemistry, molecular biology, genetics, and recombinant DNA. These principles are necessary to understanding the basic mechanisms of life and anchor the biological knowledge that is required to understand many of the challenges in everyday life, from human health and disease to loss of biodiversity and environmental quality.
The word biology means, "the science of life", from the Greek bios, …
The word biology means, "the science of life", from the Greek bios, life, and logos, word or knowledge. Therefore, Biology is the science of Living Things. That is why Biology is sometimes known as Life Science.
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BI102A is a survey course that introduces the discipline of molecular biology …
BI102A is a survey course that introduces the discipline of molecular biology and genetics, exploring topics including cell division, protein production, inheritance and gene regulation. This book focuses on putting those topics into an appropriate context for students who are not biology majors.
BI101A is a survey course that introduces the discipline of cellular biology, …
BI101A is a survey course that introduces the discipline of cellular biology, exploring topics including the scientific method, parts of a cell, and how cells function. This book focuses on putting those topics into an appropriate context for students who are not biology majors.
General Biology is intended to leave the student with an integrated view …
General Biology is intended to leave the student with an integrated view of the living world including the nature of sciences, evolution of biological organization, composition and organization of living substances, metabolism, control, reproduction, heredity and ecological relationships. This class meets the A.A. degree lab science requirement in the State of Washington.Login: guest_oclPassword: ocl
The topic of this video module is genetic basis for variation among …
The topic of this video module is genetic basis for variation among humans. The main learning objective is that students will learn the genetic mechanisms that cause variation among humans (parents and children, brothers and sisters) and how to calculate the probability that two individuals will have an identical genetic makeup. This module does not require many prerequisites, only a general knowledge of DNA as the genetic material, as well as a knowledge of meiosis.
Deals with the specific functions of neurons, the interactions of neurons in …
Deals with the specific functions of neurons, the interactions of neurons in development, and the organization of neuronal ensembles to produce behavior, by functional analysis of mutations and molecular analysis of their genes. Concentrates on work with nematodes, fruit flies, mice, and humans.
The principles of genetics with application to the study of biological function …
The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease.
This course introduces the parallel evolution of life and the environment. Life …
This course introduces the parallel evolution of life and the environment. Life processes are influenced by chemical and physical processes in the atmosphere, hydrosphere, cryosphere and the solid earth. In turn, life can influence chemical and physical processes on our planet. This course explores the concept of life as a geological agent and examines the interaction between biology and the earth system during the roughly 4 billion years since life first appeared.
Students are challenged to think as biomedical engineers and brainstorm ways to …
Students are challenged to think as biomedical engineers and brainstorm ways to administer medication to a patient who is unable to swallow. They learn about the advantages and disadvantages of current drug delivery methods—oral, injection, topical, inhalation and suppository—and pharmaceutical design considerations, including toxicity, efficacy, size, solubility/bioavailability and drug release duration. They apply their prior knowledge about human anatomy, the circulatory system, polymers, crystals and stoichiometry to real-world biomedical applications. A Microsoft® PowerPoint® presentation and worksheets are provided. This lesson prepares students for the associated activity in which they create and test large-size drug encapsulation prototypes to provide the desired delayed release and duration timing.
Fundamental principles of biochemistry. Analysis of the mode of action and structure …
Fundamental principles of biochemistry. Analysis of the mode of action and structure of regulatory, binding, and catalytic proteins. The tools and analytical methods that biochemists use to dissect biological problems. Analysis of the mode of action and structure of regulatory, binding, and catalytic proteins.
Students operate mock 3D bioprinters in order to print tissue constructs of …
Students operate mock 3D bioprinters in order to print tissue constructs of bone, muscle and skin for a fictitious trauma patient, Bill. The model bioprinters are made from ordinary materials— cardboard, dowels, wood, spools, duct tape, zip ties and glue (constructed by the teacher or the students)—and use squeeze bags of icing to lay down tissue layers. Student groups apply what they learned about biological tissue composition and tissue engineering in the associated lesson to design and fabricate model replacement tissues. They tangibly learn about the technical aspects and challenges of 3D bioprinting technology, as well as great detail about the complex cellular composition of tissues. At activity end, teams present their prototype designs to the class.
This course explores recent historical and anthropological approaches to the study of …
This course explores recent historical and anthropological approaches to the study of life, in both medicine and biology. After grounding our conversation in accounts of natural history and medicine that predate the rise of biology as a discipline, we explore modes of theorizing historical and contemporary bioscience. Drawing on the work of historian William Coleman, we examine the forms, functions, and transformations of biological and medical objects of study. Along the way we treat the history of heredity, molecular biology, race, medicine in the colonies and the metropole, and bioeconomic exchange. We read anthropological literature on old and new forms of biopower, at scales from the molecular to the organismic to the global. The course includes readings from the HASTS Common Exam List. The aim of this seminar is to train students to be participants in scholarly debates in the humanities, social sciences, and natural sciences about the nature of life, the body, and biomedicine.
Students set up and run the experiments they designed in the Population …
Students set up and run the experiments they designed in the Population Growth in Yeasts associated lesson, using simple yeast-molasses cultures in test tubes. Population growth is indicated by the amount of respiration occurring in the cultures, which in turn is indicated by the growth of carbon dioxide bubbles trapped within the culture tubes. Using this method, students test for a variety of environmental influences, such as temperature, food supply and pH.
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