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Bacteria Transformation
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Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Kimberly Anderson
Matthew Zelisko
Date Added:
09/18/2014
The Benefits of Biodiversity
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Students toss coins to determine what traits a set of mouse parents possess, such as fur color, body size, heat tolerance, and running speed. Then they use coin tossing to determine the traits a mouse pup born to these parents possesses. Then they compare these physical features to features that would be most adaptive in several different environmental conditions. Finally, students consider what would happen to the mouse offspring if those environmental conditions were to change: which mice would be most likely to survive and produce the next generation?

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
10/14/2015
Bioethics, Spring 2009
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CC BY-NC-SA
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This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers.

Subject:
Arts and Humanities
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Hare, Caspar
Jones, David
Date Added:
01/01/2009
Biotechnology: Can It Help in Making the Desert Green?
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CC BY-NC-SA
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This learning video introduces high school students to a topic they would not ordinarily study in school, biotechnology, and to different applications of biotechnology that relate to the main theme of the module - making the desert greener. After reviewing traditional methods used for manipulating plants to produce desired traits, students will learn about the methods of making transgenic plants. Dr. Ziad discusses a real world problem that is critical in his country, Jordan, where much of the land is desert. A prerequisite to this video lesson is some background in biology.

Subject:
Botany
Genetics
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Ziad W. Jaradat, PhD
Date Added:
07/02/2021
Bug Hunt
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“Bug Hunt” uses NetLogo software and simulates an insect population that is preyed on by birds. There are six speeds of bugs from slow to fast and the bird tries to catch as many insects as possible in a certain amount of time. Students are able to see the results graphed as the average insect speed over time, the current bug population and the number of insects caught. There are two variations to try for the predator, one where the predator pursues the prey and one where the predator stays still and captures insects that pass nearby. In the first case the “bird” catches the slow insects and the faster ones survive, reproduce and pass genes on. The average speed of bug should increase over time. In the second case the faster bugs come near to the bird more often than the slow ones. The slow ones survive more, reproduce and pass their genes on.

Subject:
Biology
Genetics
Material Type:
Simulation
Provider:
National Science Teachers Association (NSTA)
Provider Set:
NGSS@NSTA
Author:
Wilensky, Uri
Date Added:
07/07/2021
Chemicals in the Environment: Toxicology and Public Health (BE.104J), Spring 2005
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CC BY-NC-SA
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This course addresses the challenges of defining a relationship between exposure to environmental chemicals and human disease. Course topics include epidemiological approaches to understanding disease causation; biostatistical methods; evaluation of human exposure to chemicals, and their internal distribution, metabolism, reactions with cellular components, and biological effects; and qualitative and quantitative health risk assessment methods used in the U.S. as bases for regulatory decision-making. Throughout the term, students consider case studies of local and national interest.

Subject:
Environmental Science
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Sherley, James
Date Added:
01/01/2005
Classifying Animals by Appearance Versus DNA Sequence
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CC BY-NC-SA
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The topic of this video module is how to classify animals based on how closely related they are. The main learning objective is that students will learn how to make phylogenetic trees based on both physical characteristics and on DNA sequence. Students will also learn why the objective and quantitative nature of DNA sequencing is preferable when it come to classifying animals based on how closely related they are. Knowledge prerequisites to this lesson include that students have some understanding of what DNA is and that they have a familiarity with the base-pairing rules and with writing a DNA sequence.

Subject:
Biology
Genetics
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Megan E. Rokop
Date Added:
07/02/2021
Clipbirds
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This variation on the classic bird beak activity demonstrates variation of beak size within a population and shows how the proportion of big-, medium-, and small-beaked birds changes in response to the available types of food. The “birds” with binder clip “beaks” live in Clipland where the large population becomes divided into two smaller populations by a mountain range. Popcorn, lima beans and marbles are the three types of food available in the two areas. Food is spread out for the birds to eat and then after 15 seconds it is counted to see whether birds have gathered enough food to survive. The big billed birds need to eat more than the medium and small billed birds to survive and each bird needs to eat more than the minimum amount of food for survival to be able to reproduce. Four years pass during the simulation and students are asked to describe what happened to the Clipbird populations and what they think caused the changes. A link to Rosemary and Peter Grant’s research on finch populations in the Galapagos is identified for those teachers who want to connect the simulation to a real life example.

Subject:
Biology
Genetics
Material Type:
Activity/Lab
Provider:
National Science Teachers Association (NSTA)
Provider Set:
NGSS@NSTA
Author:
Al Janulaw, Judy Scotchmoor
Date Added:
07/07/2021
Cognitive and Behavioral Genetics, Spring 2001
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CC BY-NC-SA
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How genetics can add to our understanding of cognition, language, emotion, personality, and behavior. Use of gene mapping to estimate risk factors for psychological disorders and variation in behavioral and personality traits. Mendelian genetics, genetic mapping techniques, and statistical analysis of large populations and their application to particular studies in behavioral genetics. Topics also include environmental influence on genetic programs, evolutionary genetics, and the larger scientific, social, ethical, and philosophical implications.

Subject:
Biology
Genetics
Psychology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Nedivi, Elly
Pinker, Steve
Date Added:
01/01/2001
Color Variation over Time in Rock Pocket Mouse Populations
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This activity provides an introduction to natural selection and the role of genetic variation by asking students to analyze illustrations of rock pocket mouse populations (dark/light fur) on different color substrates in the Sonoran Desert (light/dark) over time. Based on this evidence, and what they learn about variation and natural selection in the accompanying short film, students use this evidence to explain the change in the rock pocket mouse populations on the lava flow (dark substrate) over time. This is one of several classroom activities, focusing on related topics and varying in complexity, built around the short film. This ten minute film shows adaptive changes in rock pocket mouse populations, demonstrating the process of natural selection and can be accessed at http://www.hhmi.org/biointeractive/making-fittest-natural-selection-and-adaptation. The film is also available as an interactive video with embedded questions, which test students’ understanding as they watch the film.

Subject:
Genetics
Material Type:
Lesson Plan
Provider:
National Science Teachers Association (NSTA)
Provider Set:
NGSS@NSTA
Author:
Mary Colvard
Date Added:
07/07/2021
Computation for Biological Engineers, Fall 2006
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CC BY-NC-SA
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This course covers the analytical, graphical, and numerical methods supporting the analysis and design of integrated biological systems. Topics include modularity and abstraction in biological systems, mathematical encoding of detailed physical problems, numerical methods for solving the dynamics of continuous and discrete chemical systems, statistics and probability in dynamic systems, applied local and global optimization, simple feedback and control analysis, statistics and probability in pattern recognition.

Subject:
Genetics
Statistics and Probability
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Alm, Eric
Date Added:
01/01/2006
DNA Build
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Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Date Added:
09/18/2014
DNA Forensics and Color Pigments
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Students perform DNA forensics using food coloring to enhance their understanding of DNA fingerprinting, restriction enzymes, genotyping and DNA gel electrophoresis. They place small drops of different food coloring ("water-based paint") on strips of filter paper and then place one paper strip end in water. As water travels along the paper strips, students observe the pigments that compose the paint decompose into their color components. This is an example of the chromatography concept applied to DNA forensics, with the pigments in the paint that define the color being analogous to DNA fragments of different lengths.

Subject:
Engineering
Life Science
Genetics
Physics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
DNA: The Human Body Recipe
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As a class, students work through an example showing how DNA provides the "recipe" for making our body proteins. They see how the pattern of nucleotide bases (adenine, thymine, guanine, cytosine) forms the double helix ladder shape of DNA, and serves as the code for the steps required to make genes. They also learn some ways that engineers and scientists are applying their understanding of DNA in our world.

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Lesson Plan
Teaching/Learning Strategy
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Frank Burkholder
Jessica Todd
Malinda Schaefer Zarske
Date Added:
09/18/2014
Design of Medical Devices and Implants, Spring 2006
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CC BY-NC-SA
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This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants.

Subject:
Health, Medicine and Nursing
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Spector, Myron
Yannas, Ioannis
Date Added:
01/01/2006
Discovering Genes Associated with Diseases and Traits in Dogs
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CC BY-NC-SA
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In this video module, students learn how scientists use genetic information from dogs to find out which gene (out of all 20,000 dog genes) is associated with any specific trait or disease of interest. This method involves comparing hundreds of dogs with the trait to hundreds of dogs not displaying the trait, and examining which position on the dog DNA is correlated with the trait (i.e. has one DNA sequence in dogs with the trait but another DNA sequence in dogs not displaying the trait). Students will also learn something about the history of dog breeds and how this history helps us find genes.

Subject:
Biology
Genetics
Zoology
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Elinor Karlsson
Date Added:
07/02/2021
Don't Be a Square
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After watching video clips from the Harry Potter and the Goblet of Fire movie, students explore the use of Punnett squares to predict genetic trait inheritance. The objective of this lesson is to articulate concepts related to genetics through direct immersive interaction based on the theme, The Science Behind Harry Potter. Students' interest is piqued by the use of popular culture in the classroom.

Subject:
Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
Rachel Howser
Date Added:
09/18/2014
Elements of Mechanical Design, Spring 2009
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CC BY-NC-SA
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This is an advanced course on modeling, design, integration and best practices for use of machine elements such as bearings, springs, gears, cams and mechanisms. Modeling and analysis of these elements is based upon extensive application of physics, mathematics and core mechanical engineering principles (solid mechanics, fluid mechanics, manufacturing, estimation, computer simulation, etc.). These principles are reinforced via (1) hands-on laboratory experiences wherein students conduct experiments and disassemble machines and (2) a substantial design project wherein students model, design, fabricate and characterize a mechanical system that is relevant to a real world application. Students master the materials via problems sets that are directly related to, and coordinated with, the deliverables of their project. Student assessment is based upon mastery of the course materials and the student's ability to synthesize, model and fabricate a mechanical device subject to engineering constraints (e.g. cost and time/schedule).

Subject:
Engineering
Manufacturing
Genetics
Chemistry
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Culpepper, Martin
Date Added:
01/01/2009
Engineering Nature: DNA Visualization and Manipulation
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Students are introduced to genetic techniques such as DNA electrophoresis and imaging technologies used for molecular and DNA structure visualization. In the field of molecular biology and genetics, biomedical engineering plays an increasing role in the development of new medical treatments and discoveries. Engineering applications of nanotechnology such as lab-on-a-chip and deoxyribonucleic acid (DNA) microarrays are used to study the human genome and decode the complex interactions involved in genetic processes.

Subject:
Engineering
Life Science
Genetics
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
Engineering Out of Harry Situations: The Science Behind Harry Potter
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Under the "The Science Behind Harry Potter" theme, a succession of diverse complex scientific topics are presented to students through direct immersive interaction. Student interest is piqued by the incorporation of popular culture into the classroom via a series of interactive, hands-on Harry Potter/movie-themed lessons and activities. They learn about the basics of acid/base chemistry (invisible ink), genetics and trait prediction (parseltongue trait in families), and force and projectile motion (motion of the thrown remembrall). In each lesson and activity, students are also made aware of the engineering connections to these fields of scientific study.

Subject:
Engineering
Life Science
Genetics
Mathematics
Chemistry
Physics
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
Rachel Howser
Date Added:
09/18/2014
Evolving TCE Biodegraders
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A hypothetical scenario is introduced in which the class is asked to apply their understanding of the forces that drive natural selection to prepare a proposal along with an environmental consulting company to help clean up an area near their school that is contaminated with trichloroethylene (TCE). Students use the Avida-ED software application to test hypotheses for evolving (engineering) a strain of bacteria that can biodegrade TCE, resulting in a non-hazardous clean-up solution. Conduct this design challenge activity after completion of the introduction to digital evolution activity, Studying Evolution with Digital Organisms.

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Amy Lark
Louise Mead
Robert Pennock
Wendy Johnson
Date Added:
09/18/2014
Experimental Microbial Genetics, Fall 2008
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CC BY-NC-SA
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In this class, students engage in independent research projects to probe various aspects of the physiology of the bacteriumĺĘPseudomonas aeruginosa PA14, an opportunistic pathogen isolated from the lungs of cystic fibrosis patients. Students use molecular genetics to examine survival in stationary phase, antibiotic resistance, phase variation, toxin production, and secondary metabolite production. Projects aim to discover the molecular basis for these processes using both classical and cutting-edge techniques. These include plasmid manipulation, genetic complementation, mutagenesis, PCR, DNA sequencing, enzyme assays, and gene expression studies. Instruction and practice in written and oral communication are also emphasized. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented. Legal Notice

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Croal, Laura
Laub, Michael
Melvold, Janis
Newman, Dianne
Date Added:
01/01/2008
Fabulous Fibonacci and his Nifty Numbers (2016-17)
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CC BY-NC
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Studying the Fibonacci Sequence is our entry point for studying Heredity: Inheritance and variation of traits.

Subject:
Genetics
Material Type:
Lesson Plan
Unit of Study
Provider:
Lane County STEM Hub
Provider Set:
Content in Context SuperLessons
Author:
Jill Neider
John Whisler
Date Added:
07/07/2021
The Fountain of Life: From Dolly to Customized Embryonic Stem Cells, Fall 2007
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During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which have proved to involve reversible alterations to both DNA and to proteins that bind DNA, are known as epigenetic, to distinguish them from genetic alterations to DNA sequence. In this course we will explore such epigenetic changes and study different approaches that can return a differentiated cell to an embryonic state in a process referred to as epigenetic reprogramming, which will ultimately allow generation of patient-specific stem cells and application to regenerative therapy. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Meissner, Alexander
Date Added:
01/01/2007
Freshman Seminar: Structural Basis of Genetic Material: Nucleic Acids, Fall 2005
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CC BY-NC-SA
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Since the discovery of the structure of the DNA double helix in 1953 by Watson and Crick, the information on detailed molecular structures of DNA and RNA, namely, the foundation of genetic material, has expanded rapidly. This discovery is the beginning of the "Big Bang" of molecular biology and biotechnology. In this seminar, students discuss, from a historical perspective and current developments, the importance of pursuing the detailed structural basis of genetic materials.

Subject:
Biology
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Zhang, Shuguang
Date Added:
01/01/2005
Gene Expression - The Basics
Unrestricted Use
CC BY
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Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.

Subject:
Genetics
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Ariel Paul
George Emanuel
John Blanco
Kathy Perkins
Mike Klymkowsky
Tom Perkins
Date Added:
08/20/2012
Gene Machine: The Lac Operon
Unrestricted Use
CC BY
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Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Genetics
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Spiegelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
Gene Machine: The Lac Operon (AR)
Unrestricted Use
CC BY
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Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Genetics
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Speigelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
The Genetic Basis of Inheritance and Variation
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CC BY-NC-SA
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The topic of this video module is genetic basis for variation among humans. The main learning objective is that students will learn the genetic mechanisms that cause variation among humans (parents and children, brothers and sisters) and how to calculate the probability that two individuals will have an identical genetic makeup. This module does not require many prerequisites, only a general knowledge of DNA as the genetic material, as well as a knowledge of meiosis.

Subject:
Biology
Genetics
Material Type:
Lecture
Provider:
MIT
Provider Set:
MIT Blossoms
Author:
Amjad Mahasneh
Date Added:
07/02/2021
Genetic Neurobiology, Fall 2005
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CC BY-NC-SA
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Deals with the specific functions of neurons, the interactions of neurons in development, and the organization of neuronal ensembles to produce behavior, by functional analysis of mutations and molecular analysis of their genes. Concentrates on work with nematodes, fruit flies, mice, and humans.

Subject:
Biology
Genetics
Psychology
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Littleton, Troy
Quinn, William
Date Added:
01/01/2005
Genetics, Fall 2004
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CC BY-NC-SA
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The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease.

Subject:
Education
Life Science
Biology
Genetics
Material Type:
Activity/Lab
Assessment
Diagram/Illustration
Full Course
Homework/Assignment
Lecture Notes
Student Guide
Syllabus
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Fink, Gerald
Kaiser, Chris
Mischke, Michelle
Samson, Leona
Date Added:
01/01/2004
Genomic Medicine, Spring 2004
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CC BY-NC-SA
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This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. Throughout the semester, emphasis will return to issues surrounding the context of genomics in medicine including: what does a physician need to know? what sorts of questions will s/he likely encounter from patients? how should s/he respond? Lecturers will guide the student through real world patient-doctor interactions. Outcome considerations and socioeconomic implications of personalized medicine are also discussed. The first part of the course introduces key basic concepts of molecular biology, computational biology, and genomics. Continuing in the informatics applications portion of the course, lecturers begin each lecture block with a scenario, in order to set the stage and engage the student by showing: why is this important to know? how will the information presented be brought to bear on medical practice? The final section presents the ethical, legal, and social issues surrounding genomic medicine. A vision of how genomic medicine relates to preventative care and public health is presented in a discussion forum with the students where the following questions are explored: what is your level of preparedness now? what challenges must be met by the healthcare industry to get to where it needs to be?

Subject:
Health, Medicine and Nursing
Genetics
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Kohane, Isaac
Date Added:
01/01/2004
Heredity Mix n Match
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Students randomly select jelly beans (or other candy) that represent genes for several human traits such as tongue-rolling ability and eye color. Then, working in pairs (preferably of mixed gender), students randomly choose new pairs of jelly beans from those corresponding to their own genotypes. The new pairs are placed on toothpicks to represent the chromosomes of the couple's offspring. Finally, students compare genotypes and phenotypes of parents and offspring for all the "couples" in the class. In particular, they look to see if there are cases where parents and offspring share the exact same genotype and/or phenotype, and consider how the results would differ if they repeated the simulation using more than four traits.

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
09/26/2008
Imaging DNA Structure
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Students are introduced to the latest imaging methods used to visualize molecular structures and the method of electrophoresis that is used to identify and compare genetic code (DNA). Students should already have basic knowledge of genetics, DNA (DNA structure, nucleotide bases), proteins and enzymes. The lesson begins with a discussion to motivate the need for imaging techniques and DNA analysis, which prepares students to participate in the associated two-part activity: 1) students each choose an imaging method to research (from a provided list of molecular imaging methods), 2) they research basic information about electrophoresis.

Subject:
Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
Inside the DNA
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Students conduct their own research to discover and understand the methods designed by engineers and used by scientists to analyze or validate the molecular structure of DNA, proteins and enzymes, as well as basic information about gel electrophoresis and DNA identification. In this computer-based activity, students investigate particular molecular imaging technologies, such as x-ray, atomic force microscopy, transmission electron microscopy, and create short PowerPoint presentations that address key points. The presentations include their own explanations of the difference between molecular imaging and gel electrophoresis.

Subject:
Engineering
Genetics
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
Introduction to Biological Engineering Design, Spring 2009
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CC BY-NC-SA
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This class is a project-based introduction to the engineering of synthetic biological systems. Throughout the term, students develop projects that are responsive to real-world problems of their choosing, and whose solutions depend on biological technologies. Lectures, discussions, and studio exercises will introduce (1) components and control of prokaryotic and eukaryotic behavior, (2) DNA synthesis, standards, and abstraction in biological engineering, and (3) issues of human practice, including biological safety; security; ownership, sharing, and innovation; and ethics. Enrollment preference is given to freshmen. This subject was originally developed and first taught in Spring 2008 by Drew Endy and Natalie Kuldell. Many of Drew's materials are used in this Spring 2009 version, and are included with his permission. This OCW Web site is based on the OpenWetWare class Wiki, found at OpenWetWare: 20.020 (S09)

Subject:
Biology
Genetics
Chemistry
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Kuldell, Natalie
Date Added:
01/01/2009
Introduction to Evolutionary Computation
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Educational Use
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Students are introduced to the concepts of evolution by natural selection and digital evolution software. They learn about the field of evolutionary computation, which applies the principles of natural selection to solve engineering design problems. They learn the similarities and differences between natural selection and the engineering design process.

Subject:
Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Wendy Johnson
Date Added:
09/18/2014
Introduction to Genetic Engineering and Its Applications
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Educational Use
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Students learn how engineers apply their understanding of DNA to manipulate specific genes to produce desired traits, and how engineers have used this practice to address current problems facing humanity. They learn what genetic engineering means and examples of its applications, as well as moral and ethical problems related to its implementation. Students fill out a flow chart to list the methods to modify genes to create GMOs and example applications of bacteria, plant and animal GMOs.

Subject:
Engineering
Genetics
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Kimberly Anderson
Matthew Zelisko
Date Added:
09/18/2014