This course focuses on works that caught the popular imagination in the past or present. It emphasizes texts that are related by genre, theme or style. The books studied in this course vary from semester to semester, and the topic for Fall 2006 is Detective Fictions.

What is a "life" when it's written down? How does memory inform the present? Why are memoirs so popular? This course will address these questions and others, considering the relationship between biography, autobiography, and memoir and between personal and social themes. We will closely examine some recent memoirs: Tobias Wolff's This Boy's Life, Barack Obama's Dreams From My Father, Edwidge Danticat's Brother, I'm Dying, Ayaan Hirsi Ali's Infidel, and Alison Bechdel's Fun Home. Students will write two brief papers: a critical essay and an experiment in memoir.As a "Sampling," this class offers 6 units, with a strong emphasis on close reading, group discussion, focused writing, and research and presentation skills.

If you’re a coastal engineer, ecologist or planner, then this is the course for you. You already know that engineering and ecological principles are not enough to realize nature-friendly solutions in practice. You need people on your side!

In this course you will learn how to build a relevant coalition of stakeholders to support the design and implementation of ecosystem-based hydraulic infrastructures. After learning basic stakeholder mapping and game theory techniques, you will apply Social Design Principles to a Building with Nature ecosystem-based design case. This will equip you to identify promising collaborative arrangements for your engineering or planning practice.

The course builds on the previous Building with Nature MOOC, which explored the use of natural materials and ecological processes in achieving effective and sustainable hydraulic infrastructure designs, distilling Engineering and Ecological Design Principles. In this course, the missing element of Social Design Principles are developed and taught.

You’ll learn from renowned Dutch engineers and international environmental scientists, who work at the technical- governance interface. Iconic examples such as the Maasvlakte II expansion to Rotterdam Harbor and the Delfland Sand Engine Mega-nourishment serve as study material. The challenges in designing and implementing these nature-friendly hydraulic infrastructures are explored by the eminent professors who were responsible for their genesis.

Join us in becoming one of the new generation of engineers, ecologists and planners who see the Building with Nature integrated design approach as critical to hydraulic engineering, nature and society.

An introduction to major Biblical texts including Genesis, Exodus, Job, the prophetic and historic books of the Old Testament, and the Gospels and Epistles. Stresses the place of the Bible as foundation text for central religious, ethical, and political thinking. Comparative readings in related traditions, ancient, Near Eastern, and Middle Eastern. Investigation of the Bible as influence in later narrative, philosophic, and artistic traditions.

While big data infiltrates all walks of life, most firms have not changed sufficiently to meet the challenges that come with it. In this course, you will learn how to develop a big data strategy, transform your business model and your organization.

This course will enable professionals to take their organization and their own career to the next level, regardless of their background and position.

Professionals will learn how to be in charge of big data instead of being subject to it. In particular, they will become familiar with tools to:

assess their current situation regarding potential big data-induced changes of a disruptive nature,
identify their options for successfully integrating big data in their strategy, business model and organization, or if not possible, how to exit quickly with as little loss as possible, and
strengthen their own position and that of their organization in our digitalized knowledge economy
The course will build on the concepts of product life cycles, the business model canvas, organizational theory and digitalized management jobs (such as Chief Digital Officer or Chief Informatics Officer) to help you find the best way to deal with and benefit from big data induced changes.

This course explores the physical, ecological, technological, political, economic, and cultural implications of big plans and mega-urban landscapes in a global context. It uses local and international case studies to understand the process of making major changes to urban landscape and city fabric, and to regional landscape systems. It includes lectures by leading practitioners. The assignments consider planning and design strategies across multiple scales and time frames.

This course is offered for graduate students who are interested in the interdisciplinary study of bio-inspired structures. The intent is to introduce students to newly inspired modern advanced structures and their applications. It aims to link traditional advanced composites to bio-inspired structures and to discuss their generic properties. A link between materials design, strength and structural behavior at different levels (material, element, structural and system levels) is made. For each level, various concepts will be introduced. The importance of structural, dynamic, thermodynamic and kinetic theories related to such processing is highlighted. The pedagogy is based on active learning and a balance of guest lectures and hands-on activities.

Biomechatronics is a contraction of biomechanics and mechatronics. In this course the function and coordination of the human motion apparatus is the central focus, and the design of assistive devices for the support of the function of the motion apparatus.

Have you ever asked what “biobased” means or wondered about the key aspects in developing and commercializing biobased products? This course will answer those questions and more; highlighting the opportunities, hurdles, and driving forces of the bioeconomy.

Today’s industries face enormous global challenges when it comes to the fossil-based economy. Fossil resources are no longer a desirable feedstock for many products and governments’ climate goals put various limitations to its usage. Moreover, consumer perception has become an increasingly important factor. With biobased products as an alternative to the fossil-based economy, the bioeconomy can provide viable solutions to these challenges.

The course describes the different types of biomass, the methods of refinery and typical conversion technologies used for biobased products. You’ll also engage in a study of the practical and real-life examples emerging in the market: biopolymers, bioenergy, bioflavours, and biosurfactants.

The course has been developed by a team of experts from seven different institutions and universities in three different countries, all sharing their personal perspectives on the opportunities and challenges faced by the biobased industry. The three top-ranked institutions Delft University of Technology, RWTH Aachen University, and Wageningen University & Research offer additional, more advanced courses to continue your learning journey:

Industrial Biotechnology: a more advanced course that digs deeper into engineering aspects of bio-based products.
MicroMasters Chemistry and Technology for Sustainability: Help drive the transition from fossil sources to renewable energy ones and engineer a biobased future.
Sustainable Development: The Water-Energy-Food Nexus: Introduction to sustainable development and its relation to the Water-Energy-Food Nexus.

This course focuses on the interaction of chemical engineering, biochemistry, and microbiology. Mathematical representations of microbial systems are featured among lecture topics. Kinetics of growth, death, and metabolism are also covered. Continuous fermentation, agitation, mass transfer, and scale-up in fermentation systems, and enzyme technology round out the subject material.

The course, which spans two thirds of a semester, provides students with a research-inspired laboratory experience that introduces standard biochemical techniques in the context of investigating a current and exciting research topic, acquired resistance to the cancer drug Gleevec. Techniques include protein expression, purification, and gel analysis, PCR, site-directed mutagenesis, kinase activity assays, and protein structure viewing. This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format. Acknowledgments Development of this course was funded through an HHMI Professors grant to Professor Catherine L. Drennan.

Considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. Focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control.

Each term, the class selects a new set of professional journal articles on bioengineering topics of current research interest. Some papers are chosen because of particular content, others are selected because they illustrate important points of methodology. Each week, one student leads the discussion, evaluating the strengths, weaknesses, and importance of each paper. Subject may be repeated for credit a maximum of four terms. Letter grade given in the last term applies to all accumulated units of 16.459.

This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers.

This course is designed for advanced undergraduate and graduate students with an interest in using primary research literature to discuss and learn about current research around sulfur biogeochemistry and astrobiology.

Imagine you are a salesman needing to visit 100 cities connected by a set of roads. Can you do it while stopping in each city only once? Even a supercomputer working at 1 trillion operations per second would take longer than the age of the universe to find a solution when considering each possibility in turn. In 1994, Leonard Adleman published a paper in which he described a solution, using the tools of molecular biology, for a smaller 7-city example of this problem. His paper generated enormous scientific and public interest, and kick-started the field of Biological Computing, the main subject of this discussion based seminar course. Students will analyze the Adleman paper, and the papers that preceded and followed it, with an eye for identifying the engineering and scientific aspects of each paper, emphasizing the interplay of these two approaches in the field of Biological Computing. This course is appropriate for both biology and non-biology majors. Care will be taken to fill in any knowledge gaps for both scientists and engineers.

This page, presented by MIT and made available online via the university's Open Courseware site, presents a series of materials on biological engineering. Topics include introduction to biological engineering design, systems microbiology, computation for biological engineers and molecular principles of biomaterials. Materials are at both the undergraduate and graduate school levels. OpenCourseWare is free educational material online. Video lectures, assignments and exams are included. No registration or enrollment is required to use the materials.

This course illustrates how knowledge and principles of biology, biochemistry, and engineering are integrated to create new products for societal benefit. It uses a case study format to examine recently developed products of pharmaceutical and biotechnology industries: how a product evolves from initial idea, through patents, testing, evaluation, production, and marketing. Emphasizes scientific and engineering principles; the responsibility scientists, engineers, and business executives have for the consequences of their technology; and instruction and practice in written and oral communication. The topic focus of this class will vary from year to year. This version looks at inflammation underlying many diseases, specifically its role in cancer, diabetes, and cardiovascular disease.

This course covers sensing and measurement for quantitative molecular/cell/tissue analysis, in terms of genetic, biochemical, and biophysical properties. Methods include light and fluorescence microscopies; electro-mechanical probes such as atomic force microscopy, laser and magnetic traps, and MEMS devices; and the application of statistics, probability and noise analysis to experimental data.

In this course problems from biological engineering are used to develop structured computer programming skills and explore the theory and practice of complex systems design and construction.