This is an intermediate workshop designed for students who have a basic understanding of the principles of theatrical design and who want a more intensive study of costume design and the psychology of clothing. Students develop designs that emerge through a process of character analysis, based on the script and directorial concept. Period research, design, and rendering skills are fostered through practical exercises. Instruction in basic costume construction, including drafting and draping, provide tools for students to produce final projects.

Study of an area of current interest in theoretical computer science. Topic varies from term to term. This course is a study of Behavior of Algorithms and covers an area of current interest in theoretical computer science. The topics vary from term to term. During this term, we discuss rigorous approaches to explaining the typical performance of algorithms with a focus on the following approaches: smoothed analysis, condition numbers/parametric analysis, and subclassing inputs.

In 2008, the Beijing Urban Design Studio will focus on the issue of Beijing's urban transformation under the theme of de-industrialization, by preparing an urban design and development plan for the Shougang (Capital Steel Factory) site. This studio will address whether portions of the old massive factory infrastructure can be preserved as a national industrial heritage site embedded into future new development; how to balance the cultural and recreational value of the site with environmental challenges; as well as how to use the site for urban development. A special focus of the studio will be to consider development approaches that minimize energy utilization. To research these questions, students will be asked to interact with clients from the factory, local residents, city officials and experts on transportation, environment, energy and real estate. They will assess strategic options for the steel factory and propose comprehensive plans for the design and development of the brownfield site.

This course focuses on works that caught the popular imagination in the past or present. It emphasizes texts that are related by genre, theme or style. The books studied in this course vary from semester to semester, and the topic for Fall 2006 is Detective Fictions.

What is a "life" when it's written down? How does memory inform the present? Why are memoirs so popular? This course will address these questions and others, considering the relationship between biography, autobiography, and memoir and between personal and social themes. We will closely examine some recent memoirs: Tobias Wolff's This Boy's Life, Barack Obama's Dreams From My Father, Edwidge Danticat's Brother, I'm Dying, Ayaan Hirsi Ali's Infidel, and Alison Bechdel's Fun Home. Students will write two brief papers: a critical essay and an experiment in memoir.As a "Sampling," this class offers 6 units, with a strong emphasis on close reading, group discussion, focused writing, and research and presentation skills.

An introduction to major Biblical texts including Genesis, Exodus, Job, the prophetic and historic books of the Old Testament, and the Gospels and Epistles. Stresses the place of the Bible as foundation text for central religious, ethical, and political thinking. Comparative readings in related traditions, ancient, Near Eastern, and Middle Eastern. Investigation of the Bible as influence in later narrative, philosophic, and artistic traditions.

This course explores the physical, ecological, technological, political, economic, and cultural implications of big plans and mega-urban landscapes in a global context. It uses local and international case studies to understand the process of making major changes to urban landscape and city fabric, and to regional landscape systems. It includes lectures by leading practitioners. The assignments consider planning and design strategies across multiple scales and time frames.

This course is offered for graduate students who are interested in the interdisciplinary study of bio-inspired structures. The intent is to introduce students to newly inspired modern advanced structures and their applications. It aims to link traditional advanced composites to bio-inspired structures and to discuss their generic properties. A link between materials design, strength and structural behavior at different levels (material, element, structural and system levels) is made. For each level, various concepts will be introduced. The importance of structural, dynamic, thermodynamic and kinetic theories related to such processing is highlighted. The pedagogy is based on active learning and a balance of guest lectures and hands-on activities.

This course focuses on the interaction of chemical engineering, biochemistry, and microbiology. Mathematical representations of microbial systems are featured among lecture topics. Kinetics of growth, death, and metabolism are also covered. Continuous fermentation, agitation, mass transfer, and scale-up in fermentation systems, and enzyme technology round out the subject material.

The course, which spans two thirds of a semester, provides students with a research-inspired laboratory experience that introduces standard biochemical techniques in the context of investigating a current and exciting research topic, acquired resistance to the cancer drug Gleevec. Techniques include protein expression, purification, and gel analysis, PCR, site-directed mutagenesis, kinase activity assays, and protein structure viewing. This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format. Acknowledgments Development of this course was funded through an HHMI Professors grant to Professor Catherine L. Drennan.

Considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. Focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control.

Each term, the class selects a new set of professional journal articles on bioengineering topics of current research interest. Some papers are chosen because of particular content, others are selected because they illustrate important points of methodology. Each week, one student leads the discussion, evaluating the strengths, weaknesses, and importance of each paper. Subject may be repeated for credit a maximum of four terms. Letter grade given in the last term applies to all accumulated units of 16.459.

This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers.

This course is designed for advanced undergraduate and graduate students with an interest in using primary research literature to discuss and learn about current research around sulfur biogeochemistry and astrobiology.

Imagine you are a salesman needing to visit 100 cities connected by a set of roads. Can you do it while stopping in each city only once? Even a supercomputer working at 1 trillion operations per second would take longer than the age of the universe to find a solution when considering each possibility in turn. In 1994, Leonard Adleman published a paper in which he described a solution, using the tools of molecular biology, for a smaller 7-city example of this problem. His paper generated enormous scientific and public interest, and kick-started the field of Biological Computing, the main subject of this discussion based seminar course. Students will analyze the Adleman paper, and the papers that preceded and followed it, with an eye for identifying the engineering and scientific aspects of each paper, emphasizing the interplay of these two approaches in the field of Biological Computing. This course is appropriate for both biology and non-biology majors. Care will be taken to fill in any knowledge gaps for both scientists and engineers.

This page, presented by MIT and made available online via the university's Open Courseware site, presents a series of materials on biological engineering. Topics include introduction to biological engineering design, systems microbiology, computation for biological engineers and molecular principles of biomaterials. Materials are at both the undergraduate and graduate school levels. OpenCourseWare is free educational material online. Video lectures, assignments and exams are included. No registration or enrollment is required to use the materials.

This course illustrates how knowledge and principles of biology, biochemistry, and engineering are integrated to create new products for societal benefit. It uses a case study format to examine recently developed products of pharmaceutical and biotechnology industries: how a product evolves from initial idea, through patents, testing, evaluation, production, and marketing. Emphasizes scientific and engineering principles; the responsibility scientists, engineers, and business executives have for the consequences of their technology; and instruction and practice in written and oral communication. The topic focus of this class will vary from year to year. This version looks at inflammation underlying many diseases, specifically its role in cancer, diabetes, and cardiovascular disease.

This course covers sensing and measurement for quantitative molecular/cell/tissue analysis, in terms of genetic, biochemical, and biophysical properties. Methods include light and fluorescence microscopies; electro-mechanical probes such as atomic force microscopy, laser and magnetic traps, and MEMS devices; and the application of statistics, probability and noise analysis to experimental data.

In this course problems from biological engineering are used to develop structured computer programming skills and explore the theory and practice of complex systems design and construction.

This course covers the principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Tissue and organ regeneration. Design of implants and prostheses based on control of biomaterials-tissue interactions. Comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Criteria for restoration of physiological function for tissues and organs.