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Bacteria Transformation
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Educational Use
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Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Kimberly Anderson
Matthew Zelisko
Date Added:
09/18/2014
The Benefits of Biodiversity
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Educational Use
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Students toss coins to determine what traits a set of mouse parents possess, such as fur color, body size, heat tolerance, and running speed. Then they use coin tossing to determine the traits a mouse pup born to these parents possesses. Then they compare these physical features to features that would be most adaptive in several different environmental conditions. Finally, students consider what would happen to the mouse offspring if those environmental conditions were to change: which mice would be most likely to survive and produce the next generation?

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mary R. Hebrank
Date Added:
10/14/2015
Biology
Unrestricted Use
CC BY
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Full Course
Date Added:
07/18/2021
Biology, Genetics, Genes and Proteins, Eukaryotic Transcription
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:List the steps in eukaryotic transcriptionDiscuss the role of RNA polymerases in transcriptionCompare and contrast the three RNA polymerasesExplain the significance of transcription factors

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
OpenStax College
Date Added:
07/18/2021
Biology, Genetics, Genes and Proteins, Prokaryotic Transcription
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:List the different steps in prokaryotic transcriptionDiscuss the role of promoters in prokaryotic transcriptionDescribe how and when transcription is terminated

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
OpenStax College
Date Added:
07/18/2021
Biology, Genetics, Genes and Proteins, The Genetic Code
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CC BY-NC
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By the end of this section, you will be able to:Explain the “central dogma” of protein synthesisDescribe the genetic code and how the nucleotide sequence prescribes the amino acid and the protein sequence

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
OpenStax College
Date Added:
07/18/2021
Biology, Genetics, Mendel's Experiments and Heredity, Laws of Inheritance
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CC BY-NC
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By the end of this section, you will be able to:Explain Mendel’s law of segregation and independent assortment in terms of genetics and the events of meiosisUse the forked-line method and the probability rules to calculate the probability of genotypes and phenotypes from multiple gene crossesExplain the effect of linkage and recombination on gamete genotypesExplain the phenotypic outcomes of epistatic effects between genes

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
OpenStax College
Date Added:
07/18/2021
Biology, The Cell, Cell Reproduction, Cell Division
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:Describe the structure of prokaryotic and eukaryotic genomesDistinguish between chromosomes, genes, and traitsDescribe the mechanisms of chromosome compaction

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
OpenStax College
Date Added:
07/18/2021
Biomedical Devices for the Eyes
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Educational Use
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Students examine the structure and function of the human eye, learning some amazing features about our eyes, which provide us with sight and an understanding of our surroundings. Students also learn about some common eye problems and the biomedical devices and medical procedures that resolve or help to lessen the effects of these vision deficiencies, including vision correction surgery.

Subject:
Anatomy/Physiology
Applied Science
Engineering
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Lesley Herrmann
Malinda Schaefer Zarske
William Surles
Date Added:
09/18/2014
DNA Build
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Educational Use
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Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Date Added:
09/18/2014
DNA: The Human Body Recipe
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Educational Use
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As a class, students work through an example showing how DNA provides the "recipe" for making our body proteins. They see how the pattern of nucleotide bases (adenine, thymine, guanine, cytosine) forms the double helix ladder shape of DNA, and serves as the code for the steps required to make genes. They also learn some ways that engineers and scientists are applying their understanding of DNA in our world.

Subject:
Applied Science
Engineering
Genetics
Life Science
Material Type:
Activity/Lab
Lesson Plan
Teaching/Learning Strategy
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Frank Burkholder
Jessica Todd
Malinda Schaefer Zarske
Date Added:
09/18/2014
Directed Evolution: Engineering Biocatalysts, Spring 2008
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CC BY-NC-SA
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Enzymes, nature's catalysts, are remarkable biomolecules capable of extraordinary specificity and selectivity. Directed evolution has been used to produce enzymes with many unique properties, including altered substrate specificity, thermal stability, organic solvent resistance, and enantioselectivity--selectivity of one stereoisomer over another. The technique of directed evolution comprises two essential steps: mutagenesis of the gene encoding the enzyme to produce a library of variants, and selection of a particular variant based on its desirable catalytic properties. In this course we will examine what kinds of enzymes are worth evolving and the strategies used for library generation and enzyme selection. We will focus on those enzymes that are used in the synthesis of drugs and in biotechnological applications. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Love, Kerry
Date Added:
01/01/2008
Genetics, Fall 2004
Conditional Remix & Share Permitted
CC BY-NC-SA
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The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease.

Subject:
Biology
Education
Genetics
Life Science
Material Type:
Activity/Lab
Assessment
Diagram/Illustration
Full Course
Homework/Assignment
Lecture Notes
Student Guide
Syllabus
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Fink, Gerald
Kaiser, Chris
Mischke, Michelle
Samson, Leona
Date Added:
01/01/2004