Presents the anatomy, physiology, biochemistry, biophysics, and bioengineering of the gastrointestinal tract and associated pancreatic, liver, and biliary systems. Emphasis on the molecular and pathophysiological basis of disease where known. Covers gross and microscopic pathology and clinical aspects. Formal lectures given by core faculty, with some guest lectures by local experts. Selected seminars conducted by students with supervision of faculty. Permission of instructor required. (Only HST students may register under HST.120, graded P/D/F.) The most recent knowledge of the anatomy, physiology, biochemistry, biophysics, and bioengineering of the gastrointestinal tract and the associated pancreatic, liver and biliary tract systems is presented and discussed. Gross and microscopic pathology and the clinical aspects of important gastroenterological diseases are then presented, with emphasis on integrating the molecular, cellular and pathophysiological aspects of the disease processes to their related symptoms and signs.

This course introduces incoming students in the Master in City Planning (MCP) program to the theory and history of planning in the public interest. It relies primarily on challenging real-world cases to highlight persistent dilemmas, the power and limits of planning, the multiple roles in which planners find themselves in communities around the globe, and the political, ethical, and practical dilemmas that planners face as they try to be effective. As such, the course provides an introduction to the major ideas and debates that define what the field labels ‰ŰĎplanning theory,‰Ű as well as a (necessarily) condensed global history of modern planning. Courses in planning history, politics, and ethics--often several of them--are required in all accredited graduate programs in planning in the U.S. Gateway: Planning Action combines those contents, with a stronger focus on real-world cases than more conventional lecture-based planning theory and history courses at other schools. It also adds several opportunities to strengthen hands-on professional competencies, especially in communication.

The purpose of the course is to cultivate the sensibilities necessary for effective planning practice. This objective rests on one key assumption: that a set of key sensibilities creates the right mindset for practice.

This course draws on different disciplines, conceptual frameworks, and methodological approaches to examine gender in relation to health, including public health practice, epidemiologic research, health policy, and clinical application. It discusses a variety of health-related issues that illustrate global, international, domestic, and historical perspectives, while considering other social determinants of health as well, including social class and race.

Does it matter in education whether or not you've got a Y chromosome? You bet it does. In this discussion-based seminar, we will explore why males vastly outrank females in math and science and career advancements (particularly in academia), and why girls get better grades and go to college more often than boys. Do the sexes have different learning styles? Are women denied advanced opportunities in academia and the workforce? How do family life and family decisions affect careers for both men and women?

The course will focus primarily on contemporary discourses concerning gender inequality. Most of the readings assigned will be recent articles published in U.S. and British media capturing the latest thinking and research on gender inequality in the workplace. The class will be highly interactive combining case studies, videos, debates, guest speakers, and in-class simulations.

What can we learn about science and technology--and what can we do with that knowledge? Who are we" in these questions?--whose knowledge and expertise gets made into public policy, new medicines, topics of cultural and political discourse, science education, and so on? How can expertise and lay knowledge about science and technology be reconciled in a democratic society? How can we make sense of the interactions of living and non-living, humans and non-humans, individual and collectivities in the production of scientific knowledge and technologies? The course takes these questions as entry points into an ever-growing body of work to which feminist, anti-racist, and other critical analysts and activists have made significant contributions. The course also takes these questions as an invitation to practice challenging the barriers of expertise, gender, race, class, and place that restrict wider access to and understanding of the production of scientific knowledge and technologies. In that spirit, students participate in an innovative, problem-based learning (PBL) approach that allows them to shape their own directions of inquiry and develop their skills as investigators and prospective teachers. At the same time the PBL cases engage students' critical faculties as they learn about existing analyses of gender, race, and the complexities of science and technology, guided by individualized bibliographies co-constructed with the instructors and by the projects of the other students. Students from all fields and levels of preparation are encouraged to join the course."

This course includes an introduction to the anthropological study of human sexuality, gender constructs, and the sociocultural systems that these are embedded in. Examines current critiques of Western philosophical and psychological traditions, and cross-cultural variability and universals of gender and sexuality.

This course examines relationships between identity and participation in Japanese popular culture as a way of understanding the changing character of media, capitalism, fan communities, and culture. It emphasizes contemporary popular culture and theories of gender, sexuality, race, and the workings of power and value in global culture industries. Topics include manga (comic books), hip-hop and other popular music, anime and feature films, video games, contemporary literature, and online communication. Students present analyses and develop a final project based on a particular aspect of gender and popular culture.

This course explores stereotypes associated with Asian women in colonial, nationalist, state-authoritarian, and global/diasporic narratives about gender and power. Students will read ethnography, cultural studies, and history, and view films to examine the politics and circumstances that create and perpetuate the representation of Asian women as dragon ladies, lotus blossoms, despotic tyrants, desexualized servants, and docile subordinates. Students are introduced to the debates about Orientalism, gender, and power.

This subject explores the legal history of the United States as a gendered system. It examines how women have shaped the meanings of American citizenship through pursuit of political rights such as suffrage, jury duty, and military service, how those political struggles have varied for across race, religion, and class, as well as how the legal system has shaped gender relations for both women and men through regulation of such issues as marriage, divorce, work, reproduction, and the family. The course readings will draw from primary and secondary materials in American history, as well as some court cases. However, the focus of the class is on the broader relationship between law and society, and no technical legal knowledge is required or assumed.

Diagnostic studies and discussion of their implications for the theory of the structure and general circulation of the Earth's atmosphere. Includes some discussion of the validation and use of general circulation models as atmospheric analogs.

This course provides concepts and frameworks for understanding the potential impact of information technology (IT) on business strategy and performance. We will examine how some firms make IT a strategic asset while other firms struggle to realize value from IT investments. The course focuses on the implications of increased digitization for defining business strategies and operating models, and explores the roles of both general managers and IT executives in using IT to achieve operational excellence and business agility. Topics include business operating models, IT investment and prioritization, business strategy and IT alignment, the design and governance of digitized processes, and the role of the IT unit. Draws heavily on research and case studies from MIT Sloan Center for Information Systems Research. Restricted to graduate students.

Deals with the specific functions of neurons, the interactions of neurons in development, and the organization of neuronal ensembles to produce behavior, by functional analysis of mutations and molecular analysis of their genes. Concentrates on work with nematodes, fruit flies, mice, and humans.

The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease.

This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. Throughout the semester, emphasis will return to issues surrounding the context of genomics in medicine including: what does a physician need to know? what sorts of questions will s/he likely encounter from patients? how should s/he respond? Lecturers will guide the student through real world patient-doctor interactions. Outcome considerations and socioeconomic implications of personalized medicine are also discussed. The first part of the course introduces key basic concepts of molecular biology, computational biology, and genomics. Continuing in the informatics applications portion of the course, lecturers begin each lecture block with a scenario, in order to set the stage and engage the student by showing: why is this important to know? how will the information presented be brought to bear on medical practice? The final section presents the ethical, legal, and social issues surrounding genomic medicine. A vision of how genomic medicine relates to preventative care and public health is presented in a discussion forum with the students where the following questions are explored: what is your level of preparedness now? what challenges must be met by the healthcare industry to get to where it needs to be?

This course will focus on understanding aspects of modern technology displaying exponential growth curves and the impact on global quality of life through a weekly updated class project integrating knowledge and providing practical tools for political and business decision-making concerning new aspects of bioengineering, personalized medicine, genetically modified organisms, and stem cells. Interplays of economic, ethical, ecological, and biophysical modeling will be explored through multi-disciplinary teams of students, and individual brief reports.

This course will provide a gentle, yet intense, introduction to programming using Python for highly motivated students with little or no prior experience in programming. The course will focus on planning and organizing programs, as well as the grammar of the Python programming language. The course is designed to help prepare students for 6.01 Introduction to EECS. 6.01 assumes some knowledge of Python upon entering; the course material for 6.189 has been specially designed to make sure that concepts important to 6.01 are covered. This course is offered during the Independent Activities Period (IAP), which is a special 4-week term at MIT that runs from the first week of January until the end of the month.

This course introduces the parallel evolution of life and the environment. Life processes are influenced by chemical and physical processes in the atmosphere, hydrosphere, cryosphere and the solid earth. In turn, life can influence chemical and physical processes on our planet. This course explores the concept of life as a geological agent and examines the interaction between biology and the earth system during the roughly 4 billion years since life first appeared.

This course deals with mechanics of deformation of the crust and mantle, with emphasis on the importance of different rheological descriptions: brittle, elastic, linear and nonlinear fluids, and viscoelastic.