To reinforce students' understanding of the human digestion process, the functions of …
To reinforce students' understanding of the human digestion process, the functions of several stomach and small intestine fluids are analyzed, and the concept of simulation is introduced through a short, introductory demonstration of how these fluids work. Students learn what simulation means and how it relates to the engineering process, particularly in biomedical engineering. The teacher demo requires vinegar, baking soda, water and aspirin.
The digestive system is amazing: it takes the foods we eat and …
The digestive system is amazing: it takes the foods we eat and breaks them into smaller components that our body can use for energy, cell repair and growth. This lesson introduces students to the main parts of the digestive system and how they interact. In addition, students learn about some of the challenges astronauts face when trying to eat in outer space.
Enzymes, nature's catalysts, are remarkable biomolecules capable of extraordinary specificity and selectivity. …
Enzymes, nature's catalysts, are remarkable biomolecules capable of extraordinary specificity and selectivity. Directed evolution has been used to produce enzymes with many unique properties, including altered substrate specificity, thermal stability, organic solvent resistance, and enantioselectivity--selectivity of one stereoisomer over another. The technique of directed evolution comprises two essential steps: mutagenesis of the gene encoding the enzyme to produce a library of variants, and selection of a particular variant based on its desirable catalytic properties. In this course we will examine what kinds of enzymes are worth evolving and the strategies used for library generation and enzyme selection. We will focus on those enzymes that are used in the synthesis of drugs and in biotechnological applications. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
In this video module, students learn how scientists use genetic information from …
In this video module, students learn how scientists use genetic information from dogs to find out which gene (out of all 20,000 dog genes) is associated with any specific trait or disease of interest. This method involves comparing hundreds of dogs with the trait to hundreds of dogs not displaying the trait, and examining which position on the dog DNA is correlated with the trait (i.e. has one DNA sequence in dogs with the trait but another DNA sequence in dogs not displaying the trait). Students will also learn something about the history of dog breeds and how this history helps us find genes.
Scientists who are working to discover new medicines often use robots to …
Scientists who are working to discover new medicines often use robots to prepare samples of cells, allowing them to test chemicals to identify those that might be used to treat diseases. Students will meet a scientist who works to identify new medicines. She created free software that ''looks'' at images of cells and determines which images show cells that have responded to the potential medicines. Students will learn about how this technology is currently enabling research to identify new antibiotics to treat tuberculosis. Students will complete hands-on activities that demonstrate how new medicines can be discovered using robots and computer software, starring the student as ''the computer.'' In the process, the students learn about experimental design, including positive and negative controls.
Through a teacher-led discussion, students realize that the food energy plants obtain …
Through a teacher-led discussion, students realize that the food energy plants obtain comes from sunlight via the plant process of photosynthesis. They learn what photosynthesis is, at an age-appropriate level of detail and vocabulary, and then begin to question how we know that photosynthesis occurs, if we can't see it happening. Elodea is a common water plant that students can use to directly observe evidence of photosynthesis. When Elodea is placed in a glass beaker near a good light source, bubbles of oxygen will be released as products of photosynthesis. By counting the number of bubbles that rise to the surface in a five-minute period, students can compare the photosynthetic activity of Elodea in the presence of high and low light levels.
Students learn about the amazing adaptations of the ptarmigan to the alpine …
Students learn about the amazing adaptations of the ptarmigan to the alpine tundra. They focus one adaptation, the feathered feet of the ptarmigan, and ask whether the feathers serve to only keep the feet warm or to also provide the bird with floatation capability. They create model ptarmigan feet, with and without feathers, and test the hypothesis on the function of the feathers. Ultimately, students make a claim about whether the feathers provide floatation and support this claim with their testing evidence.
In the first part of the activity, each student chews a piece …
In the first part of the activity, each student chews a piece of gum until it loses its sweetness, and then leaves the gum to dry for several days before weighing it to determine the amount of mass lost. This mass corresponds to the amount of sugar in the gum, and can be compared to the amount stated on the package label. In the second part of the activity, students work in groups to design and conduct new experiments based on questions of their own choosing. These questions arise naturally from observations during the first experiment, and from students' own experiences with and knowledge of the many varieties of chewing and bubble gums available.
After watching video clips from the Harry Potter and the Goblet of …
After watching video clips from the Harry Potter and the Goblet of Fire movie, students explore the use of Punnett squares to predict genetic trait inheritance. The objective of this lesson is to articulate concepts related to genetics through direct immersive interaction based on the theme, The Science Behind Harry Potter. Students' interest is piqued by the use of popular culture in the classroom.
An introduction to theoretical studies of systems of many interacting components, the …
An introduction to theoretical studies of systems of many interacting components, the individual dynamics of which may be simple, but the collective dynamics of which are often nonlinear and analytically intractable. Topics vary from year to year. Format includes both pedagogical lectures and round-table reviews of current literature. Subjects of interest include: problems in natural science (e.g., geology, ecology, and biology) where quantitative theory is still in development; problems in physics, such as turbulence, that demonstrate powerful concepts such as scaling and universality; and modern computational methods for the simulation and study of such problems. Discussions in context of contemporary experimental or observational data.
An engineering and design lesson for middle school (our 7th grade standards). …
An engineering and design lesson for middle school (our 7th grade standards).
In the aftermath of a natural disaster, can you engineer a device that will keep medicine within a 40-60°F range using natural resources from the biome you live in, and/or debris created by the disaster for three days, until the Red Cross can arrive?
You are a team of relief workers in __________________after a major earthquake/tsunami has occurred. Your team lead as just told you about a young women with diabetes has been injured and needs insulin to be delivered __________ miles away (no open roads). Your team will need to research, design, and build a portable device to keep the insulin between _____ and ______ °(F/C) for _____ days. Once you return you will present the effectiveness of your device to your lead and a team other relief workers showing your both your design/device and explaining the process.
How many calories are in your favorite foods? How much exercise would …
How many calories are in your favorite foods? How much exercise would you have to do to burn off these calories? What is the relationship between calories and weight? Explore these issues by choosing diet and exercise and keeping an eye on your weight.
This lesson is about the flow of energy in ecosystems. The setting …
This lesson is about the flow of energy in ecosystems. The setting is Plimoth Plantation, a living history museum in Plymouth, Massachusetts, USA, where students will learn about the first Thanksgiving meal in America, celebrated in 1621 by early American settlers and Wampanoag Indians. By examining this meal and comparing it to a modern day Thanksgiving celebration, students will be able to explore the way in which food energy moves and is transformed in an ecosystem. The learning goals focus on the movement of energy from one feeding level to the next within a food web, the way in which energy changes form, and the inefficiency of energy transfer, which in turn affects the availability of food energy for organisms at the highest feeding level. The lesson is directed at high school level biology students. Students should be familiar already with food webs, food chains, and trophic (feeding) levels. They should also be familiar with the general equations for photosynthesis (CO2 + H2O => C6H12O6) and cell respiration (C6H12O6 => CO2 + H2O), and understand the basic purpose of these processes in nature. This lesson can be completed during one long classroom period, or can be divided over two or more class meetings. The duration of the lesson will depend on prior knowledge of the students and on the amount of time allotted for student discussion. There are no supplies required for this lesson other than the downloadable worksheets (accessed on this BLOSSOMS site), paper and some glue or tape.
The major goal of this lesson is to provide students with some …
The major goal of this lesson is to provide students with some of the tools they will need to analyze and solve the many complex problems they will face during their lifetimes. In the lesson, students learn to use Flow Charts and Feedback Diagrams to analyze a very complex problem of ecological sustainability. The lesson looks at a specific case study—from my home town in the Philippines—of the Live Reef Fish Trade now threatening survival of the Coral Reef Triangle of Southeast Asia. Live reef fish have long been traded around Southeast Asia as a luxury food item, but in recent decades trade in fish captured on coral reefs has expanded rapidly. Although the trade has provided communities with additional income, these benefits are unsustainable and have come at considerable cost to the environment. This lesson begins by having students analyze a familiar or personal problem, using Flow Charts and Feedback Diagrams, and then moves on to the application of those tools to a complex environmental problem. The lesson could be completed in a 50-minute class session, but using it over two class sessions would be preferable. Everything needed for the lesson is downloadable from the BLOSSOMS website, including blank Flow Charts and Feedback Diagrams, as well as articles on the Philippines case study from the World Wildlife Fund and the United States Agency for International Development.
This course provides a review of physical, chemical, ecological, and economic principles …
This course provides a review of physical, chemical, ecological, and economic principles used to examine interactions between humans and the natural environment. Mass balance concepts are applied to ecology, chemical kinetics, hydrology, and transportation; energy balance concepts are applied to building design, ecology, and climate change; and economic and life cycle concepts are applied to resource evaluation and engineering design. Numerical models are used to integrate concepts and to assess environmental impacts of human activities. Problem sets involve development of MATLABĺ¨ models for particular engineering applications. Some experience with computer programming is helpful but not essential.
We will cover fundamentals of ecology, considering Earth as an integrated dynamic …
We will cover fundamentals of ecology, considering Earth as an integrated dynamic system. Topics include coevolution of the biosphere, geosphere, atmosphere and oceans; photosynthesis and respiration; the hydrologic, carbon and nitrogen cycles. We will examine the flow of energy and materials through ecosystems; regulation of the distribution and abundance of organisms; structure and function of ecosystems, including evolution and natural selection; metabolic diversity; productivity; trophic dynamics; models of population growth, competition, mutualism and predation. This course is designated as Communication-Intensive; instruction and practice in oral and written communication provided. Biology is a recommended prerequisite.
Students make edible models of algal cells as a way to tangibly …
Students make edible models of algal cells as a way to tangibly understand the parts of algae that are used to make biofuels. The molecular gastronomy techniques used in this activity blend chemistry, biology and food for a memorable student experience. The models use sodium alginate, which forms a gel matrix when in contact with calcium or moderate acid, to represent the complex-carbohydrate-composed cell walls of algae. Cell walls protect the algal cell contents and can be used to make biofuels, although they are more difficult to use than the starch and oils that accumulate in algal cells. The liquid juice interior of the algal models represents the starch and oils of algae, which are easily converted into biofuels.
This activity demonstrates the effect of changes in the environment on the …
This activity demonstrates the effect of changes in the environment on the growth of plants. The plants are placed in environments such as high salinity, cold, heat, or drought and observe the different reactions (growth) of the plants to these conditions. Students discuss the desirability of breeding new types of plants that are better able to withstand these changes if they occur in the general environment. The objectives of this activity is to: 1. Plant, grow and maintain plants under different environmental treatment conditions. 2. Observe differences in plant growth between these treatments. 3. Compare the growth of treated plants with the growth of control plants
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