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Bio-Engineering: Making and Testing Model Proteins
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Students act as if they are biological engineers following the steps of the engineering design process to design and create protein models to replace the defective proteins in a child’s body. Jumping off from a basic understanding of DNA and its transcription and translation processes, students learn about the many different proteins types and what happens if protein mutations occur. Then they focus on structural, transport and defense proteins during three challenges posed by the R&D; bio-engineering hypothetical scenario. Using common classroom supplies such as paper, tape and craft sticks, student pairs design, sketch, build, test and improve their own protein models to meet specific functional requirements: to strengthen bones (collagen), to capture oxygen molecules (hemoglobin) and to capture bacteria (antibody). By designing and testing physical models to accomplish certain functional requirements, students come to understand the relationship between protein structure and function. They graph and analyze the class data, then share and compare results across all teams to determine which models were the most successful. Includes a quiz, three worksheets and a reference sheet.

Subject:
Biology
Life Science
Mathematics
Measurement and Data
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
Activities
Author:
Beth Podoll
Lauren Sako
Date Added:
06/07/2018
Biobased Products for a Sustainable (Bio)economy
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CC BY-NC-SA
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Have you ever asked what “biobased” means or wondered about the key aspects in developing and commercializing biobased products? This course will answer those questions and more; highlighting the opportunities, hurdles, and driving forces of the bioeconomy.

Today’s industries face enormous global challenges when it comes to the fossil-based economy. Fossil resources are no longer a desirable feedstock for many products and governments’ climate goals put various limitations to its usage. Moreover, consumer perception has become an increasingly important factor. With biobased products as an alternative to the fossil-based economy, the bioeconomy can provide viable solutions to these challenges.

The course describes the different types of biomass, the methods of refinery and typical conversion technologies used for biobased products. You’ll also engage in a study of the practical and real-life examples emerging in the market: biopolymers, bioenergy, bioflavours, and biosurfactants.

The course has been developed by a team of experts from seven different institutions and universities in three different countries, all sharing their personal perspectives on the opportunities and challenges faced by the biobased industry. The three top-ranked institutions Delft University of Technology, RWTH Aachen University, and Wageningen University & Research offer additional, more advanced courses to continue your learning journey:

Industrial Biotechnology: a more advanced course that digs deeper into engineering aspects of bio-based products.
MicroMasters Chemistry and Technology for Sustainability: Help drive the transition from fossil sources to renewable energy ones and engineer a biobased future.
Sustainable Development: The Water-Energy-Food Nexus: Introduction to sustainable development and its relation to the Water-Energy-Food Nexus.

Subject:
Applied Science
Biology
Environmental Science
Life Science
Material Type:
Full Course
Provider:
Delft University of Technology
Provider Set:
Delft University OpenCourseWare
Author:
Dr. A. Wahl
Dr. F. Hollmann
Prof.dr. Patricia Osseweijer
Date Added:
07/14/2021
Biochar: Measuring and Improving Soil Function
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Students learn how to manipulate the behavior of water by using biochar—a soil amendment used to improve soil functions. As a fluid, water interacts with soil in a variety of ways. It may drain though a soil’s non-solid states, or its “pores”; lay above the soil; or move across cell membranes via osmosis. In this experiment, students solve the specific problem of standing water by researching, designing, and engineering solutions that enable water to drain faster. This activity is designed for students to explore how biochar helps soils to act as “sponges” in order to retain more water.

Subject:
Life Science
Mathematics
Measurement and Data
Physical Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
Activities
Author:
Chetan Sawhney
Date Added:
09/14/2018
Biochemical Engineering, Spring 2005
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CC BY-NC-SA
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This course focuses on the interaction of chemical engineering, biochemistry, and microbiology. Mathematical representations of microbial systems are featured among lecture topics. Kinetics of growth, death, and metabolism are also covered. Continuous fermentation, agitation, mass transfer, and scale-up in fermentation systems, and enzyme technology round out the subject material.

Subject:
Biology
Chemistry
Life Science
Physical Science
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Prather, Kristala
Date Added:
01/01/2005
Biodomes
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Students explore the biosphere's environments and ecosystems, learning along the way about the plants, animals, resources and natural cycles of our planet. Over the course of lessons 2-6, students use their growing understanding of various environments and the engineering design process to design and create their own model biodome ecosystems - exploring energy and nutrient flows, basic needs of plants and animals, and decomposers. Students learn about food chains and food webs. They are introduced to the roles of the water, carbon and nitrogen cycles. They test the effects of photosynthesis and transpiration. Students are introduced to animal classifications and interactions, including carnivore, herbivore, omnivore, predator and prey. They learn about biomimicry and how engineers often imitate nature in the design of new products. As everyday applications are interwoven into the lessons, students consider why a solid understanding of one's environment and the interdependence within ecosystems can inform the choices we make and the way we engineer our communities.

Subject:
Applied Science
Biology
Engineering
Life Science
Material Type:
Activity/Lab
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christopher Valenti
Denise W. Carlson
Malinda Schaefer Zarske
Date Added:
11/11/2008
Biodomes Engineering Design Project: Lessons 2-6
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In this multi-day activity, students explore environments, ecosystems, energy flow and organism interactions by creating a scale model biodome, following the steps of the engineering design process. The Procedure section provides activity instructions for Biodomes unit, lessons 2-6, as students work through Parts 1-6 to develop their model biodome. Subjects include energy flow and food chains, basic needs of plants and animals, and the importance of decomposers. Students consider why a solid understanding of one's environment and the interdependence of an ecosystem can inform the choices we make and the way we engineer our own communities. This activity can be conducted as either a very structured or open-ended design.

Subject:
Applied Science
Ecology
Engineering
Life Science
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christopher Valenti
Denise Carlson
Katherine Beggs
Malinda Schaefer Zarske
Date Added:
10/14/2015
Bioethics, Spring 2009
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CC BY-NC-SA
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This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers.

Subject:
Arts and Humanities
Genetics
Life Science
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Hare, Caspar
Jones, David
Date Added:
01/01/2009
Biofundamentals 2.0
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CC BY-SA
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Our goal is to present the key observations and unifying concepts upon which modern biology is based; it is not a survey of all biology! Once understood, these foundational observations and concepts should enable you to approach any biological process, from disease to kindness, from a scientific perspective. To understand biological systems we need to consider them from two complementary perspectives; how they came to be (the historic, that is, evolutionary) and how their structures, traits, and behaviors are produced (the mechanistic, that is, the physicochemical)

Subject:
Biology
Life Science
Material Type:
Textbook
Provider:
University of Colorado Boulder
Provider Set:
Virtual Laboratories
Author:
Melanie M. Cooper
Michael W. Klymkowski
Date Added:
06/27/2016
Biological Computing: At the Crossroads of Engineering and Science, Spring 2005
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CC BY-NC-SA
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Imagine you are a salesman needing to visit 100 cities connected by a set of roads. Can you do it while stopping in each city only once? Even a supercomputer working at 1 trillion operations per second would take longer than the age of the universe to find a solution when considering each possibility in turn. In 1994, Leonard Adleman published a paper in which he described a solution, using the tools of molecular biology, for a smaller 7-city example of this problem. His paper generated enormous scientific and public interest, and kick-started the field of Biological Computing, the main subject of this discussion based seminar course. Students will analyze the Adleman paper, and the papers that preceded and followed it, with an eye for identifying the engineering and scientific aspects of each paper, emphasizing the interplay of these two approaches in the field of Biological Computing. This course is appropriate for both biology and non-biology majors. Care will be taken to fill in any knowledge gaps for both scientists and engineers.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Khodor, Julia
Date Added:
01/01/2005
Biological Engineering
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CC BY-NC-SA
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This page, presented by MIT and made available online via the university's Open Courseware site, presents a series of materials on biological engineering. Topics include introduction to biological engineering design, systems microbiology, computation for biological engineers and molecular principles of biomaterials. Materials are at both the undergraduate and graduate school levels. OpenCourseWare is free educational material online. Video lectures, assignments and exams are included. No registration or enrollment is required to use the materials.

Subject:
Applied Science
Education
Engineering
Life Science
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Date Added:
05/13/2011
Biological Engineering Design, Spring 2010
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CC BY-NC-SA
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This course illustrates how knowledge and principles of biology, biochemistry, and engineering are integrated to create new products for societal benefit. It uses a case study format to examine recently developed products of pharmaceutical and biotechnology industries: how a product evolves from initial idea, through patents, testing, evaluation, production, and marketing. Emphasizes scientific and engineering principles; the responsibility scientists, engineers, and business executives have for the consequences of their technology; and instruction and practice in written and oral communication. The topic focus of this class will vary from year to year. This version looks at inflammation underlying many diseases, specifically its role in cancer, diabetes, and cardiovascular disease.

Subject:
Biology
Chemistry
Life Science
Physical Science
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Banuazizi, Atissa
Breindel, Harlan
Essigmann, John
Irvine, Darrell
Poe, Mya
White, Forest
Date Added:
01/01/2010
Biological Engineering II: Instrumentation and Measurement, Fall 2006
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CC BY-NC-SA
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This course covers sensing and measurement for quantitative molecular/cell/tissue analysis, in terms of genetic, biochemical, and biophysical properties. Methods include light and fluorescence microscopies; electro-mechanical probes such as atomic force microscopy, laser and magnetic traps, and MEMS devices; and the application of statistics, probability and noise analysis to experimental data.

Subject:
Biology
Career and Technical Education
Electronic Technology
Life Science
Mathematics
Statistics and Probability
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
So, Peter
Date Added:
01/01/2006
Biological Engineering Programming, Spring 2006
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CC BY-NC-SA
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In this course problems from biological engineering are used to develop structured computer programming skills and explore the theory and practice of complex systems design and construction.

Subject:
Biology
Life Science
Material Type:
Full Course
Provider:
M.I.T.
Provider Set:
M.I.T. OpenCourseWare
Author:
Endy, Andrew
Date Added:
01/01/2006
Biology
Unrestricted Use
CC BY
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Biology is designed for multi-semester biology courses for science majors. It is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. To meet the needs of today’s instructors and students, some content has been strategically condensed while maintaining the overall scope and coverage of traditional texts for this course. Instructors can customize the book, adapting it to the approach that works best in their classroom. Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Full Course
Date Added:
07/18/2021
Biology
Unrestricted Use
CC BY
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Biology is the science that studies life, but what exactly is life? This may sound like a silly question with an obvious response, but it is not always easy to define life. For example, a branch of biology called virology studies viruses, which exhibit some of the characteristics of living entities but lack others. It turns out that although viruses can attack living organisms, cause diseases, and even reproduce, they do not meet the criteria that biologists use to define life. Consequently, virologists are not biologists, strictly speaking. Similarly, some biologists study the early molecular evolution that gave rise to life; since the events that preceded life are not biological events, these scientists are also excluded from biology in the strict sense of the term. From its earliest beginnings, biology has restled with these questions: What are the shared properties that make something “alive”? And once we know something is alive, how do we find meaningful levels of organization in its structure?

Subject:
Biology
Life Science
Material Type:
Reading
Provider:
Lumen Learning
Date Added:
07/13/2021
Biology 101A Lab Packet
Unrestricted Use
CC BY
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Lab Manual for BIO101 at Mt Hood Community College. The associated textbook is available at https://openoregon.pressbooks.pub/mhccbiology101/

Subject:
Biology
Life Science
Material Type:
Activity/Lab
Provider:
OpenOregon
Author:
Christine Anderson
Lisa Bartee
Date Added:
07/07/2021
Biology 2e
Unrestricted Use
CC BY
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Biology 2e is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications. The book also includes various types of practice and homework questions that help students understand—and apply—key concepts.

Subject:
Biology
Life Science
Material Type:
Textbook
Provider:
Rice University
Provider Set:
OpenStax College
Author:
Jung Choi
Mary Ann Clark
Matthew Douglas
Date Added:
07/07/2021
Biology, Animal Structure and Function, Animal Nutrition and the Digestive System, Digestive System Processes
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CC BY-NC
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By the end of this section, you will be able to:Describe the process of digestionDetail the steps involved in digestion and absorptionDefine eliminationExplain the role of both the small and large intestines in absorption

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
OpenStax College
Date Added:
07/18/2021
Biology, Animal Structure and Function, Animal Nutrition and the Digestive System, Digestive System Regulation
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CC BY-NC
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By the end of this section, you will be able to:Discuss the role of neural regulation in digestive processesExplain how hormones regulate digestion

Subject:
Applied Science
Biology
Life Science
Material Type:
Module
Author:
OpenStax College
Date Added:
07/18/2021