Students learn how nanoparticles can be creatively used for medical diagnostic purposes. They learn about buckminsterfullerenes, more commonly known as buckyballs, and about the potential for these complex carbon molecules to deliver drugs and other treatments into the human body. They brainstorm methods to track buckyballs in the body, then build a buckyball from pipe cleaners with a fluorescent tag to model how nanoparticles might be labeled and detected for use in a living organism. As an extension, students research and select appropriate radioisotopes for different medical applications.

This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers.

This course has been designed as a seminar to give students an understanding of how scientists with medical or scientific degrees conduct research in both hospital and academic settings. There will be interactive discussions with research clinicians and scientists about the career opportunities and research challenges in the biomedical field, which an MIT student might prepare for by obtaining an MD, PhD, or combined degrees. The seminar will be held in a case presentation format, with topics chosen from the radiological sciences, including current research in magnetic resonance imaging, positron emission tomography and other nuclear imaging techniques, and advances in radiation therapy. With the lectures as background, we will also examine alternative and related options such as biomedical engineering, medical physics, and medical engineering. We'll use as examples and points of comparisons the curriculum paths available through MIT's Department of Nuclear Science and Engineering. In past years we have given very modest assignments such as readings in advance of or after a seminar, and a short term project.

D-Lab Health provides a multidisciplinary approach to global health technology design via guest lectures and a major project based on fieldwork. We will explore the current state of global health challenges and learn how to design medical technologies that address those problems. Students may travel to Nicaragua during spring break to work with health professionals, using medical technology design kits to gain field experience for their device challenge. As a final class deliverable, you will create a product design solution to address challenges observed in the field. The resulting designs are prototyped in the summer for continued evaluation and testing.

This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants.

Scientists who are working to discover new medicines often use robots to prepare samples of cells, allowing them to test chemicals to identify those that might be used to treat diseases. Students will meet a scientist who works to identify new medicines. She created free software that ''looks'' at images of cells and determines which images show cells that have responded to the potential medicines. Students will learn about how this technology is currently enabling research to identify new antibiotics to treat tuberculosis. Students will complete hands-on activities that demonstrate how new medicines can be discovered using robots and computer software, starring the student as ''the computer.'' In the process, the students learn about experimental design, including positive and negative controls.

This course examines the growing importance of medicine in culture, economics and politics. It uses an historical approach to examine the changing patterns of disease, the causes of morbidity and mortality, the evolution of medical theory and practice, the development of hospitals and the medical profession, the rise of the biomedical research industry, and the ethics of health care in America.

All of us have felt sick at some point in our lives. Many times, we find ourselves asking, "What is the quickest way that I can start to feel better?" During this two-lesson unit, students study that question and determine which form of medicine delivery (pill, liquid, injection/shot) offers the fastest relief. This challenge question serves as a real-world context for learning all about flow rates. Students study how long various prescription methods take to introduce chemicals into our blood streams, as well as use flow rate to determine how increasing a person's heart rate can theoretically make medicines work more quickly. Students are introduced to engineering devices that simulate what occurs during the distribution of antibiotic cells in the body.

First aid is the provision of immediate care to a victim with an injury of illness, usually effected by a lay person, and performed within a limited skill range. First aid is normally performed until the injury or illness is satisfactorily dealt with (such as in the case of small cuts, minor bruises, and blisters) or until the next level of care, such as an ambulance or doctor, arrives. This book is a Canadian version of the original at Wikibooks. All references to protocols which do not comply with resuscitation standards in Canada have been removed.

During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which have proved to involve reversible alterations to both DNA and to proteins that bind DNA, are known as epigenetic, to distinguish them from genetic alterations to DNA sequence. In this course we will explore such epigenetic changes and study different approaches that can return a differentiated cell to an embryonic state in a process referred to as epigenetic reprogramming, which will ultimately allow generation of patient-specific stem cells and application to regenerative therapy. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

GEM4 VisionGEM4 has brought together researchers and professionals in major institutions across the globe with distinctly different, but complementary, expertise and facilities to address significant problems at the intersections of select topics of engineering, life sciences, technology, medicine and public health.GEM4 creates new models for interactions across scientific disciplinary boundaries whereby problems spanning the range of fundamental science to clinical studies and public health can be addressed on a global scale through strategic international partnerships.Through initial focus areas in cell and molecular biomechanics, and environmental health, in the context of select human diseases, GEM4 creates a global forum for the definition and exploration of grand challenges and scientific studies, for the cross-fertilization of ideas among engineers, life scientists and medical professionals, and for the development of novel educational tools.GEM4 ActivitiesGEM4 enables the brokering of engineers, life scientists and medical professionals with shared facilities and joint students and post-doctoral fellows to tackle major problems in the context of human health and diseases that call for state-of-the-art experimental and computational tools in cell and molecular mechanics, biology and medicine. Broad examples of problems addressed include:infectious diseases such as malaria,cancer,cardiovascular diseases,biomechanical origins of inflammation.In each of these areas, the initial emphasis has included (but will not be limited to) molecular, subcellular and cellular mechanics applied to biomedicine, where a single investigator or institution is not likely to have the full spectrum of expertise, infrastructure or resources available to cover fundamental molecular science all the way to clinical studies and societal implications. Currently, twelve institutions in North America, Europe and Asia participate in this effort as Core institutions, focusing on mechanistic studies, as well as novel methods for diagnostics, vaccines or drug development and delivery.Funds have been raised to provide a structure for coordinated studies from major organizations under the umbrella of GEM4. These funds are being used for:organization of major symposia/conferences specifically targeted at the theme areas of the initiative,training grants for student fellowships for the partner institutions,summer schools to develop teaching materials,the exchange of students and researchers,operations of a central secretariat for handling the administrative and infrastructure details for such interactions,maintenance of a web site for dissemination of information.

Examines the development of computing techniques and technology in the nineteenth and twentieth centuries, particularly critical evaluation of how the very idea of "computer" changes and evolves over time. Emphasis is on technical innovation, industrial development, social context, and the role of government. Topics include Babbage, Hollerith, differential analyzers, control systems, ENIAC, radar, operations research, computers as scientific instruments, the rise of "computer science," artificial intelligence, personal computers, and networks. Includes class visits by members of the MIT community who have made important historical contributions. This course focuses on one particular aspect of the history of computing: the use of the computer as a scientific instrument. The electronic digital computer was invented to do science, and its applications range from physics to mathematics to biology to the humanities. What has been the impact of computing on the practice of science? Is the computer different from other scientific instruments? Is computer simulation a valid form of scientific experiment? Can computer models be viewed as surrogate theories? How does the computer change the way scientists approach the notions of proof, expertise, and discovery? No comprehensive history of scientific computing has yet been written. This seminar examines scientific articles, participants' memoirs, and works by historians, sociologists, and anthropologists of science to provide multiple perspectives on the use of computers in diverse fields of physical, biological, and social sciences and the humanities. We explore how the computer transformed scientific practice, and how the culture of computing was influenced, in turn, by scientific applications.

Students are introduced to a challenge question. Towards answering the question, they generate ideas for what they need to know about medicines and how they move through our bodies, watch a few short videos to gain multiple perspectives, and then learn lecture material to obtain a basic understanding of how antibiotics kill bacteria in the human body. They learn why different forms of medicine (pill, liquid or shot) get into the blood stream at different speeds.

Students continue the research begun in the associated lesson as if they were biomedical engineers working for a pharmaceutical company. Groups each perform a simple chemical reaction (to precipitate solid calcium out of solution) to observe what may occur when Osteopontin levels drop in the body. With this additional research, students determine potential health complications that might arise from a new drug that could reduce inflammatory pain in many patients, improving their quality of life. The goal of this activity is to illustrate biomedical engineering as medical problem solving, as well as emphasize the importance of maintaining normal body chemistry.

This innovative, trans-faculty subject teaches how information technologies (IT) are reshaping and redefining the health care marketplace through improved economies of scale, greater technical efficiencies in the delivery of care to patients, advanced tools for patient education and self-care, network integrated decision support tools for clinicians, and the emergence of e-commerce in health care. Student tutorials provide an opportunity for interactive discussion. Interdisciplinary project teams comprised of Harvard and MIT graduate students in medicine, business, law, education, engineering, computer science, public health, and government collaborate to design innovative IT applications. Projects are presented during the final class. ĺĘ Starting in Spring 2010, this course will be titled Enabling Technology Innovation in Healthcare and the Life Sciences.

Introduction to Sociology 2e adheres to the scope and sequence of a typical, one-semester introductory sociology course. It offers comprehensive coverage of core concepts, foundational scholars, and emerging theories, which are supported by a wealth of engaging learning materials. The textbook presents detailed section reviews with rich questions, discussions that help students apply their knowledge, and features that draw learners into the discipline in meaningful ways. The second edition retains the book’s conceptual organization, aligning to most courses, and has been significantly updated to reflect the latest research and provide examples most relevant to today’s students. In order to help instructors transition to the revised version, the 2e changes are described within the preface.

A textbook which can be used for the field of Laboratory Medicine and Pathology, featuring digitized scans of laboratory slides which enables students to learn clinical hematology without access to a laboratory.

Students create large-scale models of microfluidic devices using a process similar to that of the PDMS and plasma bonding that is used in the creation of lab-on-a-chip devices. They use disposable foam plates, plastic bendable straws and gelatin dessert mix. After the molds have hardened overnight, they use plastic syringes to inject their model devices with colored fluid to test various flow rates. From what they learn, students are able to answer the challenge question presented in lesson 1 of this unit by writing individual explanation statements.

Students will discuss the special considerations that must be made when dealing with the human body, and will gain an appreciation for the amazing devices that have improved our quality of life. They will also explore how " čĎForm Fits Function'. This lesson should serve as a starting point for students to begin to ponder how the medical devices in their everyday lives actually work.

An exploration of colonial and postcolonial clashes between theories of healing and embodiment in the African world and those of western bio-medicine. Examines how Afro-Atlantic religious traditions have challenged western conceptions of illness, healing, and the body, and have offered alternative notions of morality, rationality, kinship, gender and sexuality. Analyzes whether contemporary western bio-medical interventions reinforce colonial or imperial power in the effort to promote global health in Africa and the African diaspora.