Through two lessons and five activities, students explore the structure and function …
Through two lessons and five activities, students explore the structure and function of cell membranes. Specific transport functions, including active and passive transport, are presented. In the legacy cycle tradition, students are motivated with a Grand Challenge question. As they study the ingress and egress of particles through membranes, students learn about quantum dots and biotechnology through the concept of intracellular engineering.
This seminar is designed to be an experimental and hands-on approach to …
This seminar is designed to be an experimental and hands-on approach to applied chemistry (as seen in cooking). Cooking may be the oldest and most widespread application of chemistry and recipes may be the oldest practical result of chemical research. We shall do some cooking experiments to illustrate some chemical principles, including extraction, denaturation, and phase changes.
This course introduces experimental biochemical and molecular techniques from a quantitative engineering …
This course introduces experimental biochemical and molecular techniques from a quantitative engineering perspective. Experimental design, data analysis, and scientific communication form the underpinnings of this subject. Three discovery-based experimental modules focus on RNA engineering, protein engineering, and cell-biomaterial engineering.This OCW site is based on the source OpenWetWare class Wiki, 20.109(S10): Laboratory Fundamentals of Biological Engineering.
Students learn about how biomedical engineers create assistive devices for persons with …
Students learn about how biomedical engineers create assistive devices for persons with fine motor skill disabilities. They learn about types of forces, balanced and unbalanced forces, and the relationship between form and function, as well as the structure of the hand. They do this by designing, building and testing their own hand "gripper" prototypes that are able to grasp and lift a 200 ml cup of sand.
This is the second in a series of majoręs biology classes covering …
This is the second in a series of majoręs biology classes covering the principles of biology. The course is an integrated study of basic concepts concerning animal biology emphasizing animal evolution, diversity, phylogeny and a comparative look at general principles of animal form and function. This course is a lab science class and students will be required to participate in weekly lab activities and document their lab work for successful course completion.
Biol & 213 is the third course of a year-long series of …
Biol & 213 is the third course of a year-long series of biology courses for Biology majors. The first third of the course surveys prokaryotes, protists, fungi, and plants, focusing on diversity, evolution, and life cycles from an evolutionary perspective. We will then describe plant anatomy, physiology, growth, responses to the environment, and reproduction, emphasizing flowering plants. We will finish with ecology, focusing on population, and community ecology and expanding outward to ecosystems and the introduction of biodiversity and conservation.
This course is the first in a three-course sequence that introduces biology …
This course is the first in a three-course sequence that introduces biology in preparation for advanced study in areas of biological science such as medicine, dentistry, cell biology, microbiology, or veterinary medicine. Biol& 211 introduces students to cellular structure and function. Major topics studied include: energy capture and utilization, cellular reproduction, inheritance, genetic mutation, protein synthesis, gene expression, and biotechnology.
This Protein Purification video lesson is intended to give students some insight …
This Protein Purification video lesson is intended to give students some insight into the process and tools that scientists and engineers use to explore proteins. It is designed to extend the knowledge of students who are already somewhat sophisticated and who have a good understanding of basic biology. The question that motivates this lesson is, ''what makes two cell types different?'' and this question is posed in several ways. Such scientific reasoning raises the experimental question: how could you study just a subset of specialized proteins that distinguish one cell type from another? Two techniques useful in this regard are considered in the lesson.
Microbiology covers the scope and sequence requirements for a single-semester microbiology course …
Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.
As a group of organisms that are too small to see and …
As a group of organisms that are too small to see and best known for being agents of disease and death, microbes are not always appreciated for the numerous supportive and positive contributions they make to the living world. Designed to support a course in microbiology, Microbiology: A Laboratory Experience permits a glimpse into both the good and the bad in the microscopic world. The laboratory experiences are designed to engage and support student interest in microbiology as a topic, field of study, and career.
This text provides a series of laboratory exercises compatible with a one-semester undergraduate microbiology or bacteriology course with a three- or four-hour lab period that meets once or twice a week. The design of the lab manual conforms to the American Society for Microbiology curriculum guidelines and takes a ground-up approach — beginning with an introduction to biosafety and containment practices and how to work with biological hazards. From there the course moves to basic but essential microscopy skills, aseptic technique and culture methods, and builds to include more advanced lab techniques. The exercises incorporate a semester-long investigative laboratory project designed to promote the sense of discovery and encourage student engagement. The curriculum is rigorous but manageable for a single semester and incorporates best practices in biology education.
This on-line open source BIOL& 260 (Microbiology) is a health sciences oriented …
This on-line open source BIOL& 260 (Microbiology) is a health sciences oriented course in microbiology. It has a laboratory component and the labs are intended to be integrated throughout the course. BIOL& 260 is intended primarily for students going in to health-related professions and will emphasize the human disease and health related areas of microbiology. Areas of microbiology such as environmental, agricultural, taxonomy or astrobiology may be mentioned but not emphasized.
Detailed analysis of the biochemical mechanisms that control the maintenance, expression, and …
Detailed analysis of the biochemical mechanisms that control the maintenance, expression, and evolution of prokaryotic and eukaryotic genomes. Topics covered in lecture and readings of relevant literature include: gene regulation, DNA replication, genetic recombination, and translation. Logic of experimental design and data analysis emphasized. Presentations include both lectures and group discussions of representative papers from the literature.
Discover what controls how fast tiny molecular motors in our body pull …
Discover what controls how fast tiny molecular motors in our body pull through a single strand of DNA. How hard can the motor pull in a tug of war with the optical tweezers? Discover what helps it pull harder. Do all molecular motors behave the same?
Discover what controls how fast tiny molecular motors in our body pull …
Discover what controls how fast tiny molecular motors in our body pull through a single strand of DNA. How hard can the motor pull in a tug of war with the optical tweezers? Discover what helps it pull harder. Do all molecular motors behave the same?
Students will predict bond polarity using electron negativity values; indicate polarity with …
Students will predict bond polarity using electron negativity values; indicate polarity with a polar arrow or partial charges; rank bonds in order of polarity; and predict molecular polarity using bond polarity and molecular shape.
Watson and Crick noted that the size of a viral genome was …
Watson and Crick noted that the size of a viral genome was insufficient to encode a protein large enough to encapsidate it and reasoned, therefore that a virus shell must be composed of multiple, but identical subunits. Today, high resolution structures of virus capsids reveal the basis of this genetic economy as a highly symmetrical structure, much like a geodesic dome composed of protein subunits. Crystallographic structures and cryo-electron microscopy reconstructions combined with molecular data are beginning to reveal how these nano-structures are built. Topics covered in the course will include basic principles of virus structure and symmetry, capsid assembly, strategies for enclosing nucleic acid, proteins involved in entry and exit, and the life cycles of well understood pathogens such as HIV, influenza, polio, and Herpes. A review of cutting edge structural methods is also covered.
This course focuses on the latest scientific developments and discoveries in the …
This course focuses on the latest scientific developments and discoveries in the field of nanomechanics, the study of forces and motion on extremely tiny (10-9 m) areas of synthetic and biological materials and structures. At this level, mechanical properties are intimately related to chemistry, physics, and quantum mechanics. Most lectures will consist of a theoretical component that will then be compared to recent experimental data (case studies) in the literature. The course begins with a series of introductory lectures that describes the normal and lateral forces acting at the atomic scale. The following discussions include experimental techniques in high resolution force spectroscopy, atomistic aspects of adhesion, nanoindentation, molecular details of fracture, chemical force microscopy, elasticity of single macromolecular chains, intermolecular interactions in polymers, dynamic force spectroscopy, biomolecular bond strength measurements, and molecular motors.
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