Introduces the design of chemical reactors via synthesis of chemical kinetics, transport …
Introduces the design of chemical reactors via synthesis of chemical kinetics, transport phenomena, and mass and energy balances. Topics: reaction mechanisms and chemical/biochemical pathways; transition-state theory; batch, plug flow and well-stirred reactors; heterogeneous and enzymatic catalysis; heat and mass transport in reactors, including diffusion to and within catalyst particles and cells or immobilized enzymes.
The topic of this video module is how to classify animals based …
The topic of this video module is how to classify animals based on how closely related they are. The main learning objective is that students will learn how to make phylogenetic trees based on both physical characteristics and on DNA sequence. Students will also learn why the objective and quantitative nature of DNA sequencing is preferable when it come to classifying animals based on how closely related they are. Knowledge prerequisites to this lesson include that students have some understanding of what DNA is and that they have a familiarity with the base-pairing rules and with writing a DNA sequence.
This variation on the classic bird beak activity demonstrates variation of beak …
This variation on the classic bird beak activity demonstrates variation of beak size within a population and shows how the proportion of big-, medium-, and small-beaked birds changes in response to the available types of food. The birds with binder clip beaks live in Clipland where the large population becomes divided into two smaller populations by a mountain range. Popcorn, lima beans and marbles are the three types of food available in the two areas. Food is spread out for the birds to eat and then after 15 seconds it is counted to see whether birds have gathered enough food to survive. The big billed birds need to eat more than the medium and small billed birds to survive and each bird needs to eat more than the minimum amount of food for survival to be able to reproduce. Four years pass during the simulation and students are asked to describe what happened to the Clipbird populations and what they think caused the changes. A link to Rosemary and Peter Grants research on finch populations in the Galapagos is identified for those teachers who want to connect the simulation to a real life example.
How genetics can add to our understanding of cognition, language, emotion, personality, …
How genetics can add to our understanding of cognition, language, emotion, personality, and behavior. Use of gene mapping to estimate risk factors for psychological disorders and variation in behavioral and personality traits. Mendelian genetics, genetic mapping techniques, and statistical analysis of large populations and their application to particular studies in behavioral genetics. Topics also include environmental influence on genetic programs, evolutionary genetics, and the larger scientific, social, ethical, and philosophical implications.
This course covers the algorithmic and machine learning foundations of computational biology …
This course covers the algorithmic and machine learning foundations of computational biology combining theory with practice. We cover both foundational topics in computational biology, and current research frontiers. We study fundamental techniques, recent advances in the field, and work directly with current large-scale biological datasets.
Study and discussion of computational approaches and algorithms for contemporary problems in …
Study and discussion of computational approaches and algorithms for contemporary problems in functional genomics. Topics include DNA chip design, experimental data normalization, expression data representation standards, proteomics, gene clustering, self-organizing maps, Boolean networks, statistical graph models, Bayesian network models, continuous dynamic models, statistical metrics for model validation, model elaboration, experiment planning, and the computational complexity of functional genomics problems.
Used for students receiving Advanced Placement credit and transfer credit. Program of …
Used for students receiving Advanced Placement credit and transfer credit. Program of study or research to be arranged with a Department faculty member. Written report required. Permission of Department required.
Concepts of Biology is designed for the introductory biology course for nonmajors …
Concepts of Biology is designed for the introductory biology course for nonmajors taught at most two- and four-year colleges. The scope, sequence, and level of the program are designed to match typical course syllabi in the market. Concepts of Biology includes interesting applications, features a rich art program, and conveys the major themes of biology.
Conservation Biology in Sub-Saharan Africa comprehensively explores the challenges and potential solutions …
Conservation Biology in Sub-Saharan Africa comprehensively explores the challenges and potential solutions to key conservation issues in Sub-Saharan Africa.
Easy to read, this lucid and accessible textbook includes fifteen chapters that cover a full range of conservation topics, including threats to biodiversity, environmental laws, and protected areas management, as well as related topics such as sustainability, poverty, and human-wildlife conflict. This rich resource also includes a background discussion of what conservation biology is, a wide range of theoretical approaches to the subject, and concrete examples of conservation practice in specific African contexts. Strategies are outlined to protect biodiversity whilst promoting economic development in the region.
In this activity, students examine how to grow plants the most efficiently. …
In this activity, students examine how to grow plants the most efficiently. They imagine that they are designing a biofuels production facility and need to know how to efficiently grow plants to use in this facility. As a means of solving this design problem, they plan a scientific experiment in which they investigate how a given variable (of their choice) affects plant growth. They then make predictions about the outcomes and record their observations after two weeks regarding the condition of the plants' stem, leaves and roots. They use these observations to guide their solution to the engineering design problem. The biological processes of photosynthesis and transpiration are briefly explained to help students make informed decisions about planning and interpreting their investigation and its results.
This online interactive module of 10 pages or frames integrates textual information, …
This online interactive module of 10 pages or frames integrates textual information, 3D molecular models, interactive molecular simulations, and embedded assessment items to guide students in understanding the copying of DNA base sequences from translation to transcription into proteins within each cell. The module divides the exercises in to Day 1 and Day 2 time frames. Teachers can view student assessment responses by assigning the module within a class created within the Molecular Workbench application. This Java-based module must be downloaded to each computer.
Students learn how the process of soil solarization is used to pasteurize …
Students learn how the process of soil solarization is used to pasteurize agricultural fields before planting crops. Soil solarization is a pest control technique in agriculture that uses the sun’s radiation to heat the soil and eliminate unwanted pests that could harm the crops. The approach is compared to other pest control methods such as fumigation and herbicide application, highlighting the respective benefits and drawbacks. In preparation for the associated hands-on activity on soil biosolarization, students learn how changing the variables involved in the solarizing process (such as the tarp material, soil water content and addition of organic matter) impacts the technique’s effectiveness. A PowerPoint® presentation and pre/post-quiz is provided.
This three-act film tells the story of the detective work that solved …
This three-act film tells the story of the detective work that solved the mystery of what caused the disappearance of the dinosaurs at the end of the Cretaceous period. Shot on location in Italy, Spain, Texas, Colorado, and North Dakota, the film traces the uncovering of key clues that led to the discovery that an asteroid struck the Earth 66 million years ago, triggering a mass extinction of animals, plants, and microorganisms. Science practices in geology, physics, biology, chemistry and paleontology all contributed to the solution to this compelling mystery. Lesson plans are included that have students identify evidence and construct an explanation to tie it together. Summary questions are included at the end and a class discussion is recommended. (This activity will be the only one evaluated in this review.) Another resource is Finding the Crater where students visit different K-T boundary sites. There are also lessons where students analyze various characteristics of the asteroid such as its size and energy, chemical data about the asteroid, and the iridium fallout from an asteroid impact. A hands-on activity where students study the differences in foraminifera fossils below and above the K-T boundary is also included as well as an article that outlines more details about each of the discoveries covered in the film. You can view the film on the website or HHMI will send you a free DVD. Lesson plans including teacher notes and a student handout can be found at http://www.hhmi.org/biointeractive/following-trail-evidence.
The principles involved in morphogenesis and the determination of complex cellular patterns …
The principles involved in morphogenesis and the determination of complex cellular patterns are examined using examples from animal systems in which the tools of genetics, molecular biology and cell biology have been applied to reveal mechanism. This graduate and advanced undergraduate level lecture and literature discussion course covers the current understanding of the molecular mechanisms that regulate animal development. Evolutionary mechanisms are emphasized as well as the discussion of relevant diseases. Vertebrate (mouse, chick, frog, fish) and invertebrate (fly, worm) models are covered. Specific topics include formation of early body plan, cell type determination, organogenesis, morphogenesis, stem cells, cloning, and issues in human development.
Considers molecular control of neural specification, formation of neuronal connections, construction of …
Considers molecular control of neural specification, formation of neuronal connections, construction of neural systems, and the contributions of experience to shaping brain structure and function. Topics include: neural induction and pattern formation, cell lineage and fate determination, neuronal migration, axon guidance, synapse formation and stabilization, activity-dependent development and critical periods, development of behavior.
This is a peer-reviewed chapter in an open access book, Human Microbiome. …
This is a peer-reviewed chapter in an open access book, Human Microbiome. This chapter is a highly technical synopsis of the relationship between the human gut microbiome and the brain, also known as the gut-microbiome-brain axis. In both medicine and nutrition, this is an expanding field of inquiry. Chemical molecules involved in this “dialogue” are examined. The author provides a brief overview of animal experiments and concludes with a discussion of the significance of the microbiome on human mental health. The chapter is clear, timely and relevant. It is a technical reading that is best suited to nurses, physicians, nutritionists, and other allied health professionals at both the undergraduate and graduate level. This chapter is also of special interest to researchers.
In a multi-week experiment, student teams gather biogas data from the mini-anaerobic …
In a multi-week experiment, student teams gather biogas data from the mini-anaerobic digesters that they build to break down different types of food waste with microbes. Using plastic soda bottles for the mini-anaerobic digesters and gas measurement devices, they compare methane gas production from decomposing hot dogs, diced vs. whole. They monitor and measure the gas production, then graph and analyze the collected data. Students learn how anaerobic digestion can be used to biorecycle waste (food, poop or yard waste) into valuable resources (nutrients, biogas, energy).
Enzymes, nature's catalysts, are remarkable biomolecules capable of extraordinary specificity and selectivity. …
Enzymes, nature's catalysts, are remarkable biomolecules capable of extraordinary specificity and selectivity. Directed evolution has been used to produce enzymes with many unique properties, including altered substrate specificity, thermal stability, organic solvent resistance, and enantioselectivity--selectivity of one stereoisomer over another. The technique of directed evolution comprises two essential steps: mutagenesis of the gene encoding the enzyme to produce a library of variants, and selection of a particular variant based on its desirable catalytic properties. In this course we will examine what kinds of enzymes are worth evolving and the strategies used for library generation and enzyme selection. We will focus on those enzymes that are used in the synthesis of drugs and in biotechnological applications. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
In this video module, students learn how scientists use genetic information from …
In this video module, students learn how scientists use genetic information from dogs to find out which gene (out of all 20,000 dog genes) is associated with any specific trait or disease of interest. This method involves comparing hundreds of dogs with the trait to hundreds of dogs not displaying the trait, and examining which position on the dog DNA is correlated with the trait (i.e. has one DNA sequence in dogs with the trait but another DNA sequence in dogs not displaying the trait). Students will also learn something about the history of dog breeds and how this history helps us find genes.
Scientists who are working to discover new medicines often use robots to …
Scientists who are working to discover new medicines often use robots to prepare samples of cells, allowing them to test chemicals to identify those that might be used to treat diseases. Students will meet a scientist who works to identify new medicines. She created free software that ''looks'' at images of cells and determines which images show cells that have responded to the potential medicines. Students will learn about how this technology is currently enabling research to identify new antibiotics to treat tuberculosis. Students will complete hands-on activities that demonstrate how new medicines can be discovered using robots and computer software, starring the student as ''the computer.'' In the process, the students learn about experimental design, including positive and negative controls.
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