This course is an introduction to the theory that tries to explain how minds are made from collections of simpler processes. It treats such aspects of thinking as vision, language, learning, reasoning, memory, consciousness, ideals, emotions, and personality. It incorporates ideas from psychology, artificial intelligence, and computer science to resolve theoretical issues such as wholes vs. parts, structural vs. functional descriptions, declarative vs. procedural representations, symbolic vs. connectionist models, and logical vs. common-sense theories of learning.

Memory is not a unitary faculty, but rather consists of multiple forms of learning that differ in their operating characteristics and neurobiological substrates. This seminar will consider current debates regarding the cognitive and neural architectures of memory, specifically focusing on recent efforts to address these controversies through application of functional neuroimaging (primarily fMRI and PET).

In this course we will discover how innovative technologies combined with profound hypotheses have given rise to our current understanding of neuroscience. We will study both new and classical primary research papers with a focus on the plasticity between synapses in a brain structure called the hippocampus, which is believed to underlie the ability to create and retrieve certain classes of memories. We will discuss the basic electrical properties of neurons and how they fire. We will see how firing properties can change with experience, and we will study the biochemical basis of these changes. We will learn how molecular biology can be used to specifically change the biochemical properties of brain circuits, and we will see how these circuits form a representation of space giving rise to complex behaviors in living animals. A special emphasis will be given to understanding why specific experiments were done and how to design experiments that will answer the questions you have about the brain. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.