By the end of this section, you will be able to:Explain pharmacogenomicsDefine polygenic
By the end of this section, you will be able to:Describe gel electrophoresisExplain molecular and reproductive cloningDescribe uses of biotechnology in medicine and agriculture
By the end of this section, you will be able to:Explain systems biologyDescribe a proteomeDefine protein signature
By the end of this section, you will be able to:Define genomicsDescribe genetic and physical mapsDescribe genomic mapping methods
By the end of this section, you will be able to:Describe three types of sequencingDefine whole-genome sequencing
By the end of this section, you will be able to:Explain how the structure of DNA reveals the replication processDescribe the Meselson and Stahl experiments
By the end of this section, you will be able to:Discuss the different types of mutations in DNAExplain DNA repair mechanisms
By the end of this section, you will be able to:Discuss the similarities and differences between DNA replication in eukaryotes and prokaryotesState the role of telomerase in DNA replication
By the end of this section, you will be able to:Explain the process of DNA replication in prokaryotesDiscuss the role of different enzymes and proteins in supporting this process
By the end of this section, you will be able to:Describe the structure of DNAExplain the Sanger method of DNA sequencingDiscuss the similarities and differences between eukaryotic and prokaryotic DNA
By the end of this section, you will be able to:Explain transformation of DNADescribe the key experiments that helped identify that DNA is the genetic materialState and explain Chargaff’s rules
By the end of this section, you will be able to:Describe how changes to gene expression can cause cancerExplain how changes to gene expression at different levels can disrupt the cell cycleDiscuss how understanding regulation of gene expression can lead to better drug design
By the end of this section, you will be able to:Explain the process of epigenetic regulationDescribe how access to DNA is controlled by histone modification
By the end of this section, you will be able to:Understand RNA splicing and explain its role in regulating gene expressionDescribe the importance of RNA stability in gene regulation
By the end of this section, you will be able to:Discuss the role of transcription factors in gene regulationExplain how enhancers and repressors regulate gene expression
By the end of this section, you will be able to:Understand the process of translation and discuss its key factorsDescribe how the initiation complex controls translationExplain the different ways in which the post-translational control of gene expression takes place
By the end of this section, you will be able to:Describe the steps involved in prokaryotic gene regulationExplain the roles of activators, inducers, and repressors in gene regulation